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EGF decreases the abundance of microRNAs that restrain oncogenic transcription factors.
Avraham R, Sas-Chen A, Manor O, Steinfeld I, Shalgi R, Tarcic G, Bossel N, Zeisel A, Amit I, Zwang Y, Enerly E, Russnes HG, Biagioni F, Mottolese M, Strano S, Blandino G, Børresen-Dale AL, Pilpel Y, Yakhini Z, Segal E, Yarden Y. Avraham R, et al. Among authors: amit i. Sci Signal. 2010 Jun 1;3(124):ra43. doi: 10.1126/scisignal.2000876. Sci Signal. 2010. PMID: 20516477
A module of negative feedback regulators defines growth factor signaling.
Amit I, Citri A, Shay T, Lu Y, Katz M, Zhang F, Tarcic G, Siwak D, Lahad J, Jacob-Hirsch J, Amariglio N, Vaisman N, Segal E, Rechavi G, Alon U, Mills GB, Domany E, Yarden Y. Amit I, et al. Nat Genet. 2007 Apr;39(4):503-12. doi: 10.1038/ng1987. Epub 2007 Feb 25. Nat Genet. 2007. PMID: 17322878
A reciprocal tensin-3-cten switch mediates EGF-driven mammary cell migration.
Katz M, Amit I, Citri A, Shay T, Carvalho S, Lavi S, Milanezi F, Lyass L, Amariglio N, Jacob-Hirsch J, Ben-Chetrit N, Tarcic G, Lindzen M, Avraham R, Liao YC, Trusk P, Lyass A, Rechavi G, Spector NL, Lo SH, Schmitt F, Bacus SS, Yarden Y. Katz M, et al. Among authors: amit i. Nat Cell Biol. 2007 Aug;9(8):961-9. doi: 10.1038/ncb1622. Epub 2007 Jul 22. Nat Cell Biol. 2007. PMID: 17643115
EGR1 and the ERK-ERF axis drive mammary cell migration in response to EGF.
Tarcic G, Avraham R, Pines G, Amit I, Shay T, Lu Y, Zwang Y, Katz M, Ben-Chetrit N, Jacob-Hirsch J, Virgilio L, Rechavi G, Mavrothalassitis G, Mills GB, Domany E, Yarden Y. Tarcic G, et al. Among authors: amit i. FASEB J. 2012 Apr;26(4):1582-92. doi: 10.1096/fj.11-194654. Epub 2011 Dec 23. FASEB J. 2012. PMID: 22198386 Free PMC article.
229 results