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High-throughput microfluidic single-cell RT-qPCR.
White AK, VanInsberghe M, Petriv OI, Hamidi M, Sikorski D, Marra MA, Piret J, Aparicio S, Hansen CL. White AK, et al. Among authors: aparicio s. Proc Natl Acad Sci U S A. 2011 Aug 23;108(34):13999-4004. doi: 10.1073/pnas.1019446108. Epub 2011 Aug 1. Proc Natl Acad Sci U S A. 2011. PMID: 21808033 Free PMC article.
Epidermal growth factor receptor (EGFR) is transcriptionally induced by the Y-box binding protein-1 (YB-1) and can be inhibited with Iressa in basal-like breast cancer, providing a potential target for therapy.
Stratford AL, Habibi G, Astanehe A, Jiang H, Hu K, Park E, Shadeo A, Buys TP, Lam W, Pugh T, Marra M, Nielsen TO, Klinge U, Mertens PR, Aparicio S, Dunn SE. Stratford AL, et al. Among authors: aparicio s. Breast Cancer Res. 2007;9(5):R61. doi: 10.1186/bcr1767. Breast Cancer Res. 2007. PMID: 17875215 Free PMC article.
Mutational evolution in a lobular breast tumour profiled at single nucleotide resolution.
Shah SP, Morin RD, Khattra J, Prentice L, Pugh T, Burleigh A, Delaney A, Gelmon K, Guliany R, Senz J, Steidl C, Holt RA, Jones S, Sun M, Leung G, Moore R, Severson T, Taylor GA, Teschendorff AE, Tse K, Turashvili G, Varhol R, Warren RL, Watson P, Zhao Y, Caldas C, Huntsman D, Hirst M, Marra MA, Aparicio S. Shah SP, et al. Among authors: aparicio s. Nature. 2009 Oct 8;461(7265):809-13. doi: 10.1038/nature08489. Nature. 2009. PMID: 19812674
Somatic mutations altering EZH2 (Tyr641) in follicular and diffuse large B-cell lymphomas of germinal-center origin.
Morin RD, Johnson NA, Severson TM, Mungall AJ, An J, Goya R, Paul JE, Boyle M, Woolcock BW, Kuchenbauer F, Yap D, Humphries RK, Griffith OL, Shah S, Zhu H, Kimbara M, Shashkin P, Charlot JF, Tcherpakov M, Corbett R, Tam A, Varhol R, Smailus D, Moksa M, Zhao Y, Delaney A, Qian H, Birol I, Schein J, Moore R, Holt R, Horsman DE, Connors JM, Jones S, Aparicio S, Hirst M, Gascoyne RD, Marra MA. Morin RD, et al. Among authors: aparicio s. Nat Genet. 2010 Feb;42(2):181-5. doi: 10.1038/ng.518. Epub 2010 Jan 17. Nat Genet. 2010. PMID: 20081860 Free PMC article.
SNVMix: predicting single nucleotide variants from next-generation sequencing of tumors.
Goya R, Sun MG, Morin RD, Leung G, Ha G, Wiegand KC, Senz J, Crisan A, Marra MA, Hirst M, Huntsman D, Murphy KP, Aparicio S, Shah SP. Goya R, et al. Among authors: aparicio s. Bioinformatics. 2010 Mar 15;26(6):730-6. doi: 10.1093/bioinformatics/btq040. Epub 2010 Feb 3. Bioinformatics. 2010. PMID: 20130035 Free PMC article.
JointSNVMix: a probabilistic model for accurate detection of somatic mutations in normal/tumour paired next-generation sequencing data.
Roth A, Ding J, Morin R, Crisan A, Ha G, Giuliany R, Bashashati A, Hirst M, Turashvili G, Oloumi A, Marra MA, Aparicio S, Shah SP. Roth A, et al. Among authors: aparicio s. Bioinformatics. 2012 Apr 1;28(7):907-13. doi: 10.1093/bioinformatics/bts053. Epub 2012 Jan 27. Bioinformatics. 2012. PMID: 22285562 Free PMC article.
Mutation discovery in regions of segmental cancer genome amplifications with CoNAn-SNV: a mixture model for next generation sequencing of tumors.
Crisan A, Goya R, Ha G, Ding J, Prentice LM, Oloumi A, Senz J, Zeng T, Tse K, Delaney A, Marra MA, Huntsman DG, Hirst M, Aparicio S, Shah S. Crisan A, et al. Among authors: aparicio s. PLoS One. 2012;7(8):e41551. doi: 10.1371/journal.pone.0041551. Epub 2012 Aug 16. PLoS One. 2012. PMID: 22916110 Free PMC article.
Multi-Omic Analysis of CIC's Functional Networks Reveals Novel Interaction Partners and a Potential Role in Mitotic Fidelity.
Takemon Y, LeBlanc VG, Song J, Chan SY, Lee SD, Trinh DL, Ahmad ST, Brothers WR, Corbett RD, Gagliardi A, Moradian A, Cairncross JG, Yip S, Aparicio SAJR, Chan JA, Hughes CS, Morin GB, Gorski SM, Chittaranjan S, Marra MA. Takemon Y, et al. Among authors: aparicio sajr. Cancers (Basel). 2023 May 17;15(10):2805. doi: 10.3390/cancers15102805. Cancers (Basel). 2023. PMID: 37345142 Free PMC article.
Mll5 is required for normal spermatogenesis.
Yap DB, Walker DC, Prentice LM, McKinney S, Turashvili G, Mooslehner-Allen K, de Algara TR, Fee J, de Tassigny Xd, Colledge WH, Aparicio S. Yap DB, et al. Among authors: aparicio s. PLoS One. 2011;6(11):e27127. doi: 10.1371/journal.pone.0027127. Epub 2011 Nov 1. PLoS One. 2011. PMID: 22069496 Free PMC article.
465 results