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Selective inhibition of Ezh2 by a small molecule inhibitor blocks tumor cells proliferation.
Proc Natl Acad Sci U S A. 2012 Dec 26;109(52):21360-5. doi: 10.1073/pnas.1210371110. Epub 2012 Dec 10.
Proc Natl Acad Sci U S A. 2012.
PMID: 23236167
Free PMC article.
Discovery and Molecular Basis of a Diverse Set of Polycomb Repressive Complex 2 Inhibitors Recognition by EED.
Li L, Zhang H, Zhang M, Zhao M, Feng L, Luo X, Gao Z, Huang Y, Ardayfio O, Zhang JH, Lin Y, Fan H, Mi Y, Li G, Liu L, Feng L, Luo F, Teng L, Qi W, Ottl J, Lingel A, Bussiere DE, Yu Z, Atadja P, Lu C, Li E, Gu J, Zhao K.
Li L, et al. Among authors: ardayfio o.
PLoS One. 2017 Jan 10;12(1):e0169855. doi: 10.1371/journal.pone.0169855. eCollection 2017.
PLoS One. 2017.
PMID: 28072869
Free PMC article.
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Application of Titration-Based Screening for the Rapid Pilot Testing of High-Throughput Assays.
Zhang JH, Kang ZB, Ardayfio O, Ho PI, Smith T, Wallace I, Bowes S, Hill WA, Auld DS.
Zhang JH, et al. Among authors: ardayfio o.
J Biomol Screen. 2014 Jun;19(5):651-60. doi: 10.1177/1087057113512151. Epub 2013 Nov 18.
J Biomol Screen. 2014.
PMID: 24246376
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Identification of orally available naphthyridine protein kinase D inhibitors.
Meredith EL, Ardayfio O, Beattie K, Dobler MR, Enyedy I, Gaul C, Hosagrahara V, Jewell C, Koch K, Lee W, Lehmann H, McKinsey TA, Miranda K, Pagratis N, Pancost M, Patnaik A, Phan D, Plato C, Qian M, Rajaraman V, Rao C, Rozhitskaya O, Ruppen T, Shi J, Siska SJ, Springer C, van Eis M, Vega RB, von Matt A, Yang L, Yoon T, Zhang JH, Zhu N, Monovich LG.
Meredith EL, et al. Among authors: ardayfio o.
J Med Chem. 2010 Aug 12;53(15):5400-21. doi: 10.1021/jm100075z.
J Med Chem. 2010.
PMID: 20684591
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