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Multi-ancestry sleep-by-SNP interaction analysis in 126,926 individuals reveals lipid loci stratified by sleep duration.
Noordam R, Bos MM, Wang H, Winkler TW, Bentley AR, Kilpeläinen TO, de Vries PS, Sung YJ, Schwander K, Cade BE, Manning A, Aschard H, Brown MR, Chen H, Franceschini N, Musani SK, Richard M, Vojinovic D, Aslibekyan S, Bartz TM, de Las Fuentes L, Feitosa M, Horimoto AR, Ilkov M, Kho M, Kraja A, Li C, Lim E, Liu Y, Mook-Kanamori DO, Rankinen T, Tajuddin SM, van der Spek A, Wang Z, Marten J, Laville V, Alver M, Evangelou E, Graff ME, He M, Kühnel B, Lyytikäinen LP, Marques-Vidal P, Nolte IM, Palmer ND, Rauramaa R, Shu XO, Snieder H, Weiss S, Wen W, Yanek LR, Adolfo C, Ballantyne C, Bielak L, Biermasz NR, Boerwinkle E, Dimou N, Eiriksdottir G, Gao C, Gharib SA, Gottlieb DJ, Haba-Rubio J, Harris TB, Heikkinen S, Heinzer R, Hixson JE, Homuth G, Ikram MA, Komulainen P, Krieger JE, Lee J, Liu J, Lohman KK, Luik AI, Mägi R, Martin LW, Meitinger T, Metspalu A, Milaneschi Y, Nalls MA, O'Connell J, Peters A, Peyser P, Raitakari OT, Reiner AP, Rensen PCN, Rice TK, Rich SS, Roenneberg T, Rotter JI, Schreiner PJ, Shikany J, Sidney SS, Sims M, Sitlani CM, Sofer T, Strauch K, Swertz MA, Taylor KD, Uitterlinden AG, van Duijn CM, Völzke H, Waldenberger M, Wallance RB, van Dijk KW, Yu C, Zonderm… See abstract for full author list ➔ Noordam R, et al. Among authors: aslibekyan s. Nat Commun. 2019 Nov 12;10(1):5121. doi: 10.1038/s41467-019-12958-0. Nat Commun. 2019. PMID: 31719535 Free PMC article.
Variants identified in a GWAS meta-analysis for blood lipids are associated with the lipid response to fenofibrate.
Aslibekyan S, Goodarzi MO, Frazier-Wood AC, Yan X, Irvin MR, Kim E, Tiwari HK, Guo X, Straka RJ, Taylor KD, Tsai MY, Hopkins PN, Korenman SG, Borecki IB, Chen YD, Ordovas JM, Rotter JI, Arnett DK. Aslibekyan S, et al. PLoS One. 2012;7(10):e48663. doi: 10.1371/journal.pone.0048663. Epub 2012 Oct 31. PLoS One. 2012. PMID: 23119086 Free PMC article.
Preliminary evidence of genetic determinants of adiponectin response to fenofibrate in the Genetics of Lipid Lowering Drugs and Diet Network.
Aslibekyan S, An P, Frazier-Wood AC, Kabagambe EK, Irvin MR, Straka RJ, Tiwari HK, Tsai MY, Hopkins PN, Borecki IB, Ordovas JM, Arnett DK. Aslibekyan S, et al. Nutr Metab Cardiovasc Dis. 2013 Oct;23(10):987-94. doi: 10.1016/j.numecd.2012.07.010. Epub 2012 Nov 11. Nutr Metab Cardiovasc Dis. 2013. PMID: 23149075 Free PMC article.
Genetic variants associated with VLDL, LDL and HDL particle size differ with race/ethnicity.
Frazier-Wood AC, Manichaikul A, Aslibekyan S, Borecki IB, Goff DC, Hopkins PN, Lai CQ, Ordovas JM, Post WS, Rich SS, Sale MM, Siscovick D, Straka RJ, Tiwari HK, Tsai MY, Rotter JI, Arnett DK. Frazier-Wood AC, et al. Among authors: aslibekyan s. Hum Genet. 2013 Apr;132(4):405-13. doi: 10.1007/s00439-012-1256-1. Epub 2012 Dec 22. Hum Genet. 2013. PMID: 23263444 Free PMC article. Clinical Trial.
SNPs located at CpG sites modulate genome-epigenome interaction.
Zhi D, Aslibekyan S, Irvin MR, Claas SA, Borecki IB, Ordovas JM, Absher DM, Arnett DK. Zhi D, et al. Among authors: aslibekyan s. Epigenetics. 2013 Aug;8(8):802-6. doi: 10.4161/epi.25501. Epub 2013 Jun 28. Epigenetics. 2013. PMID: 23811543 Free PMC article.
200 results