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1,3,8-Triazaspiro[4.5]decane-2,4-diones as efficacious pan-inhibitors of hypoxia-inducible factor prolyl hydroxylase 1-3 (HIF PHD1-3) for the treatment of anemia.
Vachal P, Miao S, Pierce JM, Guiadeen D, Colandrea VJ, Wyvratt MJ, Salowe SP, Sonatore LM, Milligan JA, Hajdu R, Gollapudi A, Keohane CA, Lingham RB, Mandala SM, DeMartino JA, Tong X, Wolff M, Steinhuebel D, Kieczykowski GR, Fleitz FJ, Chapman K, Athanasopoulos J, Adam G, Akyuz CD, Jena DK, Lusen JW, Meng J, Stein BD, Xia L, Sherer EC, Hale JJ. Vachal P, et al. Among authors: athanasopoulos j. J Med Chem. 2012 Apr 12;55(7):2945-59. doi: 10.1021/jm201542d. Epub 2012 Feb 27. J Med Chem. 2012. PMID: 22364528
Affinity-based ranking of ligands for DPP-4 from mixtures.
Adam GC, Meng J, Athanasopoulos J, Zhang X, Chapman KT. Adam GC, et al. Among authors: athanasopoulos j. Bioorg Med Chem Lett. 2007 May 1;17(9):2404-7. doi: 10.1016/j.bmcl.2007.02.040. Epub 2007 Feb 17. Bioorg Med Chem Lett. 2007. PMID: 17337342
High-throughput purification platform in support of drug discovery.
Liu M, Chen K, Christian D, Fatima T, Pissarnitski N, Streckfuss E, Zhang C, Xia L, Borges S, Shi Z, Vachal P, Tata J, Athanasopoulos J. Liu M, et al. Among authors: athanasopoulos j. ACS Comb Sci. 2012 Jan 9;14(1):51-9. doi: 10.1021/co200138h. Epub 2011 Nov 2. ACS Comb Sci. 2012. PMID: 22032344
Acute mastoiditis in a newborn with aural atresia.
Parpounas K, Bouka K, Athanasopoulos J, Lamprou M, Helmis G, Vlastos IM. Parpounas K, et al. Among authors: athanasopoulos j. Case Rep Otolaryngol. 2012;2012:459293. doi: 10.1155/2012/459293. Epub 2012 Aug 7. Case Rep Otolaryngol. 2012. PMID: 22928137 Free PMC article.