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Page 1
Early progression to active tuberculosis is a highly heritable trait driven by 3q23 in Peruvians.
Luo Y, Suliman S, Asgari S, Amariuta T, Baglaenko Y, Martínez-Bonet M, Ishigaki K, Gutierrez-Arcelus M, Calderon R, Lecca L, León SR, Jimenez J, Yataco R, Contreras C, Galea JT, Becerra M, Nejentsev S, Nigrovic PA, Moody DB, Murray MB, Raychaudhuri S. Luo Y, et al. Among authors: baglaenko y. Nat Commun. 2019 Aug 21;10(1):3765. doi: 10.1038/s41467-019-11664-1. Nat Commun. 2019. PMID: 31434886 Free PMC article.
Multimodal single-cell approaches shed light on T cell heterogeneity.
Nathan A, Baglaenko Y, Fonseka CY, Beynor JI, Raychaudhuri S. Nathan A, et al. Among authors: baglaenko y. Curr Opin Immunol. 2019 Dec;61:17-25. doi: 10.1016/j.coi.2019.07.002. Epub 2019 Aug 17. Curr Opin Immunol. 2019. PMID: 31430664 Free PMC article. Review.
Fast, sensitive and accurate integration of single-cell data with Harmony.
Korsunsky I, Millard N, Fan J, Slowikowski K, Zhang F, Wei K, Baglaenko Y, Brenner M, Loh PR, Raychaudhuri S. Korsunsky I, et al. Among authors: baglaenko y. Nat Methods. 2019 Dec;16(12):1289-1296. doi: 10.1038/s41592-019-0619-0. Epub 2019 Nov 18. Nat Methods. 2019. PMID: 31740819 Free PMC article.
Allele-specific expression changes dynamically during T cell activation in HLA and other autoimmune loci.
Gutierrez-Arcelus M, Baglaenko Y, Arora J, Hannes S, Luo Y, Amariuta T, Teslovich N, Rao DA, Ermann J, Jonsson AH; NHLBI Trans-Omics for Precision Medicine (TOPMed) Consortium; Navarrete C, Rich SS, Taylor KD, Rotter JI, Gregersen PK, Esko T, Brenner MB, Raychaudhuri S. Gutierrez-Arcelus M, et al. Among authors: baglaenko y. Nat Genet. 2020 Mar;52(3):247-253. doi: 10.1038/s41588-020-0579-4. Epub 2020 Feb 17. Nat Genet. 2020. PMID: 32066938 Free PMC article.
Multimodally profiling memory T cells from a tuberculosis cohort identifies cell state associations with demographics, environment and disease.
Nathan A, Beynor JI, Baglaenko Y, Suliman S, Ishigaki K, Asgari S, Huang CC, Luo Y, Zhang Z, Lopez K, Lindestam Arlehamn CS, Ernst JD, Jimenez J, Calderón RI, Lecca L, Van Rhijn I, Moody DB, Murray MB, Raychaudhuri S. Nathan A, et al. Among authors: baglaenko y. Nat Immunol. 2021 Jun;22(6):781-793. doi: 10.1038/s41590-021-00933-1. Epub 2021 May 24. Nat Immunol. 2021. PMID: 34031617 Free PMC article.
Single-cell eQTL models reveal dynamic T cell state dependence of disease loci.
Nathan A, Asgari S, Ishigaki K, Valencia C, Amariuta T, Luo Y, Beynor JI, Baglaenko Y, Suliman S, Price AL, Lecca L, Murray MB, Moody DB, Raychaudhuri S. Nathan A, et al. Among authors: baglaenko y. Nature. 2022 Jun;606(7912):120-128. doi: 10.1038/s41586-022-04713-1. Epub 2022 May 11. Nature. 2022. PMID: 35545678 Free PMC article.
Immunosuppression causes dynamic changes in expression QTLs in psoriatic skin.
Xiao Q, Mears J, Nathan A, Ishigaki K, Baglaenko Y, Lim N, Cooney LA, Harris KM, Anderson MS, Fox DA, Smilek DE, Krueger JG, Raychaudhuri S. Xiao Q, et al. Among authors: baglaenko y. Nat Commun. 2023 Oct 7;14(1):6268. doi: 10.1038/s41467-023-41984-2. Nat Commun. 2023. PMID: 37805522 Free PMC article.
Genetic engineering in primary human B cells with CRISPR-Cas9 ribonucleoproteins.
Wu CM, Roth TL, Baglaenko Y, Ferri DM, Brauer P, Zuniga-Pflucker JC, Rosbe KW, Wither JE, Marson A, Allen CDC. Wu CM, et al. Among authors: baglaenko y. J Immunol Methods. 2018 Jun;457:33-40. doi: 10.1016/j.jim.2018.03.009. Epub 2018 Mar 31. J Immunol Methods. 2018. PMID: 29614266 Free PMC article.
Apoptotic cell-induced AhR activity is required for immunological tolerance and suppression of systemic lupus erythematosus in mice and humans.
Shinde R, Hezaveh K, Halaby MJ, Kloetgen A, Chakravarthy A, da Silva Medina T, Deol R, Manion KP, Baglaenko Y, Eldh M, Lamorte S, Wallace D, Chodisetti SB, Ravishankar B, Liu H, Chaudhary K, Munn DH, Tsirigos A, Madaio M, Gabrielsson S, Touma Z, Wither J, De Carvalho DD, McGaha TL. Shinde R, et al. Among authors: baglaenko y. Nat Immunol. 2018 Jun;19(6):571-582. doi: 10.1038/s41590-018-0107-1. Epub 2018 May 14. Nat Immunol. 2018. PMID: 29760532 Free PMC article.
26 results