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The anti-Rac1-GTP antibody and the detection of active Rac1: a tool with a fundamental flaw.
Baker MJ, Kazanietz MG. Baker MJ, et al. Small GTPases. 2022 Jan;13(1):136-140. doi: 10.1080/21541248.2021.1920824. Epub 2021 Apr 29. Small GTPases. 2022. PMID: 33910489 Free PMC article.
Using a series of cancer cellular models, we recently demonstrated that a widely used antibody for visualizing active Rac1 (Rac1-GTP) does not recognize Rac1 but instead recognizes vimentin filaments (Baker MJ, J. Biol. Chem. 295:13698-13710, 2020). We believe that …
Using a series of cancer cellular models, we recently demonstrated that a widely used antibody for visualizing active Rac1 (Rac1-GTP) does n …
Mechanical strain stimulates COPII-dependent secretory trafficking via Rac1.
Phuyal S, Djaerff E, Le Roux AL, Baker MJ, Fankhauser D, Mahdizadeh SJ, Reiterer V, Parizadeh A, Felder E, Kahlhofer JC, Teis D, Kazanietz MG, Geley S, Eriksson L, Roca-Cusachs P, Farhan H. Phuyal S, et al. Among authors: baker mj. EMBO J. 2022 Sep 15;41(18):e110596. doi: 10.15252/embj.2022110596. Epub 2022 Aug 8. EMBO J. 2022. PMID: 35938214 Free PMC article.
233 results