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Chromosome 17 deletions and p53 gene mutations in colorectal carcinomas.
Baker SJ, Fearon ER, Nigro JM, Hamilton SR, Preisinger AC, Jessup JM, vanTuinen P, Ledbetter DH, Barker DF, Nakamura Y, White R, Vogelstein B. Baker SJ, et al. Science. 1989 Apr 14;244(4901):217-21. doi: 10.1126/science.2649981. Science. 1989. PMID: 2649981
p53: a tumor suppressor hiding in plain sight.
Baker SJ, Vogelstein B. Baker SJ, et al. J Mol Cell Biol. 2019 Jul 19;11(7):536-538. doi: 10.1093/jmcb/mjz068. J Mol Cell Biol. 2019. PMID: 31276589 Free PMC article. No abstract available.
Mutant p53 can induce tumorigenic conversion of human bronchial epithelial cells and reduce their responsiveness to a negative growth factor, transforming growth factor beta 1.
Gerwin BI, Spillare E, Forrester K, Lehman TA, Kispert J, Welsh JA, Pfeifer AM, Lechner JF, Baker SJ, Vogelstein B, et al. Gerwin BI, et al. Among authors: baker sj. Proc Natl Acad Sci U S A. 1992 Apr 1;89(7):2759-63. doi: 10.1073/pnas.89.7.2759. Proc Natl Acad Sci U S A. 1992. PMID: 1557382 Free PMC article.
Mutant p53 proteins bind DNA abnormally in vitro.
Kern SE, Kinzler KW, Baker SJ, Nigro JM, Rotter V, Levine AJ, Friedman P, Prives C, Vogelstein B. Kern SE, et al. Among authors: baker sj. Oncogene. 1991 Jan;6(1):131-6. Oncogene. 1991. PMID: 1846954
p53 functions as a cell cycle control protein in osteosarcomas.
Diller L, Kassel J, Nelson CE, Gryka MA, Litwak G, Gebhardt M, Bressac B, Ozturk M, Baker SJ, Vogelstein B, et al. Diller L, et al. Among authors: baker sj. Mol Cell Biol. 1990 Nov;10(11):5772-81. doi: 10.1128/mcb.10.11.5772-5781.1990. Mol Cell Biol. 1990. PMID: 2233717 Free PMC article.
Mutations in the p53 gene occur in diverse human tumour types.
Nigro JM, Baker SJ, Preisinger AC, Jessup JM, Hostetter R, Cleary K, Bigner SH, Davidson N, Baylin S, Devilee P, et al. Nigro JM, et al. Among authors: baker sj. Nature. 1989 Dec 7;342(6250):705-8. doi: 10.1038/342705a0. Nature. 1989. PMID: 2531845 Free article.
Knudson's hypothesis and the TP53 revolution.
Baker SJ, Kinzler KW, Vogelstein B. Baker SJ, et al. Genes Chromosomes Cancer. 2003 Dec;38(4):329. doi: 10.1002/gcc.10249. Genes Chromosomes Cancer. 2003. PMID: 14566852 No abstract available.
415 results