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A genome-wide analysis of the response to inhaled β2-agonists in chronic obstructive pulmonary disease.
Hardin M, Cho MH, McDonald ML, Wan E, Lomas DA, Coxson HO, MacNee W, Vestbo J, Yates JC, Agusti A, Calverley PM, Celli B, Crim C, Rennard S, Wouters E, Bakke P, Bhatt SP, Kim V, Ramsdell J, Regan EA, Make BJ, Hokanson JE, Crapo JD, Beaty TH, Hersh CP; ECLIPSE and COPDGene Investigators; COPDGene Investigators—clinical centers. Hardin M, et al. Among authors: bakke p. Pharmacogenomics J. 2016 Aug;16(4):326-35. doi: 10.1038/tpj.2015.65. Epub 2015 Oct 27. Pharmacogenomics J. 2016. PMID: 26503814 Free PMC article.
Evaluation of serum CC-16 as a biomarker for COPD in the ECLIPSE cohort.
Lomas DA, Silverman EK, Edwards LD, Miller BE, Coxson HO, Tal-Singer R; Evaluation of COPD Longitudinally to Identify Predictive Surrogate Endpoints (ECLIPSE) investigators. Lomas DA, et al. Thorax. 2008 Dec;63(12):1058-63. doi: 10.1136/thx.2008.102574. Epub 2008 Aug 29. Thorax. 2008. PMID: 18757456
Serum surfactant protein D is steroid sensitive and associated with exacerbations of COPD.
Lomas DA, Silverman EK, Edwards LD, Locantore NW, Miller BE, Horstman DH, Tal-Singer R; Evaluation of COPD Longitudinally to Identify Predictive Surrogate Endpoints study investigators. Lomas DA, et al. Eur Respir J. 2009 Jul;34(1):95-102. doi: 10.1183/09031936.00156508. Epub 2009 Jan 22. Eur Respir J. 2009. PMID: 19164344 Free article.
A genome-wide association study in chronic obstructive pulmonary disease (COPD): identification of two major susceptibility loci.
Pillai SG, Ge D, Zhu G, Kong X, Shianna KV, Need AC, Feng S, Hersh CP, Bakke P, Gulsvik A, Ruppert A, Lødrup Carlsen KC, Roses A, Anderson W, Rennard SI, Lomas DA, Silverman EK, Goldstein DB; ICGN Investigators. Pillai SG, et al. Among authors: bakke p. PLoS Genet. 2009 Mar;5(3):e1000421. doi: 10.1371/journal.pgen.1000421. Epub 2009 Mar 20. PLoS Genet. 2009. PMID: 19300482 Free PMC article.
CTLA4 gene polymorphisms are associated with chronic bronchitis.
Zhu G, Agusti A, Gulsvik A, Bakke P, Coxson H, Lomas DA, Silverman EK, Pillai SG; ICGN investigators. Zhu G, et al. Among authors: bakke p. Eur Respir J. 2009 Sep;34(3):598-604. doi: 10.1183/09031936.00141808. Epub 2009 Apr 22. Eur Respir J. 2009. PMID: 19386687 Free article.
Variants in FAM13A are associated with chronic obstructive pulmonary disease.
Cho MH, Boutaoui N, Klanderman BJ, Sylvia JS, Ziniti JP, Hersh CP, DeMeo DL, Hunninghake GM, Litonjua AA, Sparrow D, Lange C, Won S, Murphy JR, Beaty TH, Regan EA, Make BJ, Hokanson JE, Crapo JD, Kong X, Anderson WH, Tal-Singer R, Lomas DA, Bakke P, Gulsvik A, Pillai SG, Silverman EK. Cho MH, et al. Among authors: bakke p. Nat Genet. 2010 Mar;42(3):200-2. doi: 10.1038/ng.535. Epub 2010 Feb 21. Nat Genet. 2010. PMID: 20173748 Free PMC article.
364 results