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Page 1
The P4 Health Spectrum - A Predictive, Preventive, Personalized and Participatory Continuum for Promoting Healthspan.
Sagner M, McNeil A, Puska P, Auffray C, Price ND, Hood L, Lavie CJ, Han ZG, Chen Z, Brahmachari SK, McEwen BS, Soares MB, Balling R, Epel E, Arena R. Sagner M, et al. Among authors: balling r. Prog Cardiovasc Dis. 2017 Mar-Apr;59(5):506-521. doi: 10.1016/j.pcad.2016.08.002. Epub 2016 Aug 18. Prog Cardiovasc Dis. 2017. PMID: 27546358 Review.
Systems medicine and integrated care to combat chronic noncommunicable diseases.
Bousquet J, Anto JM, Sterk PJ, Adcock IM, Chung KF, Roca J, Agusti A, Brightling C, Cambon-Thomsen A, Cesario A, Abdelhak S, Antonarakis SE, Avignon A, Ballabio A, Baraldi E, Baranov A, Bieber T, Bockaert J, Brahmachari S, Brambilla C, Bringer J, Dauzat M, Ernberg I, Fabbri L, Froguel P, Galas D, Gojobori T, Hunter P, Jorgensen C, Kauffmann F, Kourilsky P, Kowalski ML, Lancet D, Pen CL, Mallet J, Mayosi B, Mercier J, Metspalu A, Nadeau JH, Ninot G, Noble D, Oztürk M, Palkonen S, Préfaut C, Rabe K, Renard E, Roberts RG, Samolinski B, Schünemann HJ, Simon HU, Soares MB, Superti-Furga G, Tegner J, Verjovski-Almeida S, Wellstead P, Wolkenhauer O, Wouters E, Balling R, Brookes AJ, Charron D, Pison C, Chen Z, Hood L, Auffray C. Bousquet J, et al. Among authors: balling r. Genome Med. 2011 Jul 6;3(7):43. doi: 10.1186/gm259. Genome Med. 2011. PMID: 21745417 Free PMC article.
Systems medicine approaches for the definition of complex phenotypes in chronic diseases and ageing. From concept to implementation and policies.
Bousquet J, Jorgensen C, Dauzat M, Cesario A, Camuzat T, Bourret R, Best N, Anto JM, Abecassis F, Aubas P, Avignon A, Badin M, Bedbrook A, Blain H, Bourdin A, Bringer J, Camu W, Cayla G, Costa DJ, Courtet P, Cristol JP, Demoly P, de la Coussaye JE, Fesler P, Gouzi F, Gris JC, Guillot B, Hayot M, Jeandel C, Jonquet O, Journot L, Lehmann S, Mathieu G, Morel J, Ninot G, Pelissier J, Picot MC, Radier-Pontal F, Robine JM, Rodier M, Roubille F, Sultan A, Wojtusciszyn A, Auffray C, Balling R, Barbara C, Cambon-Thomsen A, Chavannes NH, Chuchalin A, Crooks G, Dedeu A, Fabbri LM, Garcia-Aymerich J, Hajjam J, Melo Gomes E, Palkonen S, Piette F, Pison C, Price D, Samolinski B, Schunemann HJ, Sterk PJ, Yiallouros P, Roca J, Van de Perre P, Mercier J. Bousquet J, et al. Among authors: balling r. Curr Pharm Des. 2014;20(38):5928-44. doi: 10.2174/1381612820666140314115505. Curr Pharm Des. 2014. PMID: 24641234 Review.
Making sense of big data in health research: Towards an EU action plan.
Auffray C, Balling R, Barroso I, Bencze L, Benson M, Bergeron J, Bernal-Delgado E, Blomberg N, Bock C, Conesa A, Del Signore S, Delogne C, Devilee P, Di Meglio A, Eijkemans M, Flicek P, Graf N, Grimm V, Guchelaar HJ, Guo YK, Gut IG, Hanbury A, Hanif S, Hilgers RD, Honrado Á, Hose DR, Houwing-Duistermaat J, Hubbard T, Janacek SH, Karanikas H, Kievits T, Kohler M, Kremer A, Lanfear J, Lengauer T, Maes E, Meert T, Müller W, Nickel D, Oledzki P, Pedersen B, Petkovic M, Pliakos K, Rattray M, I Màs JR, Schneider R, Sengstag T, Serra-Picamal X, Spek W, Vaas LA, van Batenburg O, Vandelaer M, Varnai P, Villoslada P, Vizcaíno JA, Wubbe JP, Zanetti G. Auffray C, et al. Among authors: balling r. Genome Med. 2016 Jun 23;8(1):71. doi: 10.1186/s13073-016-0323-y. Genome Med. 2016. PMID: 27338147 Free PMC article.
A systems medicine clinical platform for understanding and managing non- communicable diseases.
Cesario A, Auffray C, Agusti A, Apolone G, Balling R, Barbanti P, Bellia A, Boccia S, Bousquet J, Cardaci V, Cazzola M, Dall'Armi V, Daraselia N, Ros LD, Bufalo AD, Ducci G, Ferri L, Fini M, Fossati C, Gensini G, Granone PM, Kinross J, Lauro D, Cascio GL, Lococo F, Lococo A, Maier D, Marcus F, Margaritora S, Marra C, Minati G, Neri M, Pasqua F, Pison C, Pristipino C, Roca J, Rosano G, Rossini PM, Russo P, Salinaro G, Shenhar S, Soreq H, Sterk PJ, Stocchi F, Torti M, Volterrani M, Wouters EF, Frustaci A, Bonassi S. Cesario A, et al. Among authors: balling r. Curr Pharm Des. 2014;20(38):5945-56. doi: 10.2174/1381612820666140314130449. Curr Pharm Des. 2014. PMID: 24641232 Review.
Erratum to: Making sense of big data in health research: towards an EU action plan.
Auffray C, Balling R, Barroso I, Bencze L, Benson M, Bergeron J, Bernal-Delgado E, Blomberg N, Bock C, Conesa A, Del Signore S, Delogne C, Devilee P, Di Meglio A, Eijkemans M, Flicek P, Graf N, Grimm V, Guchelaar HJ, Guo YK, Gut IG, Hanbury A, Hanif S, Hilgers RD, Honrado Á, Hose DR, Houwing-Duistermaat J, Hubbard T, Janacek SH, Karanikas H, Kievits T, Kohler M, Kremer A, Lanfear J, Lengauer T, Maes E, Meert T, Müller W, Nickel D, Oledzki P, Pedersen B, Petkovic M, Pliakos K, Rattray M, I Màs JR, Schneider R, Sengstag T, Serra-Picamal X, Spek W, Vaas LA, van Batenburg O, Vandelaer M, Varnai P, Villoslada P, Vizcaíno JA, Wubbe JP, Zanetti G. Auffray C, et al. Among authors: balling r. Genome Med. 2016 Nov 7;8(1):118. doi: 10.1186/s13073-016-0376-y. Genome Med. 2016. PMID: 27821178 Free PMC article. No abstract available.
Mutations in STX1B, encoding a presynaptic protein, cause fever-associated epilepsy syndromes.
Schubert J, Siekierska A, Langlois M, May P, Huneau C, Becker F, Muhle H, Suls A, Lemke JR, de Kovel CG, Thiele H, Konrad K, Kawalia A, Toliat MR, Sander T, Rüschendorf F, Caliebe A, Nagel I, Kohl B, Kecskés A, Jacmin M, Hardies K, Weckhuysen S, Riesch E, Dorn T, Brilstra EH, Baulac S, Møller RS, Hjalgrim H, Koeleman BP; EuroEPINOMICS RES Consortium; Jurkat-Rott K, Lehman-Horn F, Roach JC, Glusman G, Hood L, Galas DJ, Martin B, de Witte PA, Biskup S, De Jonghe P, Helbig I, Balling R, Nürnberg P, Crawford AD, Esguerra CV, Weber YG, Lerche H. Schubert J, et al. Among authors: balling r. Nat Genet. 2014 Dec;46(12):1327-32. doi: 10.1038/ng.3130. Epub 2014 Nov 2. Nat Genet. 2014. PMID: 25362483
Global implementation of genomic medicine: We are not alone.
Manolio TA, Abramowicz M, Al-Mulla F, Anderson W, Balling R, Berger AC, Bleyl S, Chakravarti A, Chantratita W, Chisholm RL, Dissanayake VH, Dunn M, Dzau VJ, Han BG, Hubbard T, Kolbe A, Korf B, Kubo M, Lasko P, Leego E, Mahasirimongkol S, Majumdar PP, Matthijs G, McLeod HL, Metspalu A, Meulien P, Miyano S, Naparstek Y, O'Rourke PP, Patrinos GP, Rehm HL, Relling MV, Rennert G, Rodriguez LL, Roden DM, Shuldiner AR, Sinha S, Tan P, Ulfendahl M, Ward R, Williams MS, Wong JE, Green ED, Ginsburg GS. Manolio TA, et al. Among authors: balling r. Sci Transl Med. 2015 Jun 3;7(290):290ps13. doi: 10.1126/scitranslmed.aab0194. Sci Transl Med. 2015. PMID: 26041702 Free PMC article. Review.
From hype to reality: data science enabling personalized medicine.
Fröhlich H, Balling R, Beerenwinkel N, Kohlbacher O, Kumar S, Lengauer T, Maathuis MH, Moreau Y, Murphy SA, Przytycka TM, Rebhan M, Röst H, Schuppert A, Schwab M, Spang R, Stekhoven D, Sun J, Weber A, Ziemek D, Zupan B. Fröhlich H, et al. Among authors: balling r. BMC Med. 2018 Aug 27;16(1):150. doi: 10.1186/s12916-018-1122-7. BMC Med. 2018. PMID: 30145981 Free PMC article.
251 results