Balzarini J - Search Results

1

Synthesis and cytostatic evaluation of 4-N-alkanoyl and 4-N-alkyl gemcitabine analogues.

Pulido J, Sobczak AJ, Balzarini J, Wnuk SF. Pulido J, et al. Among authors: balzarini j. J Med Chem. 2014 Jan 9;57(1):191-203. doi: 10.1021/jm401586a. Epub 2013 Dec 30. J Med Chem. 2014. PMID: 24341356 Free PMC article.

2

Anticancer and antiviral effects and inactivation of S-adenosyl-L-homocysteine hydrolase with 5'-carboxaldehydes and oximes synthesized from adenosine and sugar-modified analogues.

Wnuk SF, Yuan CS, Borchardt RT, Balzarini J, De Clercq E, Robins MJ. Wnuk SF, et al. Among authors: balzarini j. J Med Chem. 1997 May 23;40(11):1608-18. doi: 10.1021/jm960828p. J Med Chem. 1997. PMID: 9171871

3

Discovery of type II (covalent) inactivation of S-adenosyl-L-homocysteine hydrolase involving its "hydrolytic activity": synthesis and evaluation of dihalohomovinyl nucleoside analogues derived from adenosine.

Wnuk SF, Mao Y, Yuan CS, Borchardt RT, Andrei G, Balzarini J, De Clercq E, Robins MJ. Wnuk SF, et al. Among authors: balzarini j. J Med Chem. 1998 Jul 30;41(16):3078-83. doi: 10.1021/jm9801410. J Med Chem. 1998. PMID: 9685247

4

Doubly homologated dihalovinyl and acetylene analogues of adenosine: synthesis, interaction with S-adenosyl-L-homocysteine hydrolase, and antiviral and cytostatic effects.

Wnuk SF, Valdez CA, Khan J, Moutinho P, Robins MJ, Yang X, Borchardt RT, Balzarini J, De Clercq E. Wnuk SF, et al. Among authors: balzarini j. J Med Chem. 2000 Mar 23;43(6):1180-6. doi: 10.1021/jm990486y. J Med Chem. 2000. PMID: 10737751

5

Synthesis of purine and 7-deazapurine nucleoside analogues of 6-N-(4-Nitrobenzyl)adenosine; inhibition of nucleoside transport and proliferation of cancer cells.

Rayala R, Theard P, Ortiz H, Yao S, Young JD, Balzarini J, Robins MJ, Wnuk SF. Rayala R, et al. Among authors: balzarini j. ChemMedChem. 2014 Sep;9(9):2186-92. doi: 10.1002/cmdc.201402047. Epub 2014 Apr 30. ChemMedChem. 2014. PMID: 24788480 Free PMC article.

6

Wnuk SF, Yuan CS, Borchardt RT, Balzarini J, De Clercq E, Robins MJ. Wnuk SF, et al. Among authors: balzarini j. J Med Chem. 1994 Oct 14;37(21):3579-87. doi: 10.1021/jm00047a015. J Med Chem. 1994. PMID: 7932585

7

Inactivation of S-adenosyl-L-homocysteine hydrolase and antiviral activity with 5',5',6',6'-tetradehydro-6'-deoxy-6'-halohomoadenosine analogues (4'-haloacetylene analogues derived from adenosine).

Robins MJ, Wnuk SF, Yang X, Yuan CS, Borchardt RT, Balzarini J, De Clercq E. Robins MJ, et al. Among authors: balzarini j. J Med Chem. 1998 Sep 24;41(20):3857-64. doi: 10.1021/jm980163m. J Med Chem. 1998. PMID: 9748360

8

Synthesis and antiviral evaluation of 6-(alkyl-heteroaryl)furo[2,3-d]pyrimidin-2(3H)-one nucleosides and analogues with ethynyl, ethenyl, and ethyl spacers at C6 of the furopyrimidine core.

Robins MJ, Nowak I, Rajwanshi VK, Miranda K, Cannon JF, Peterson MA, Andrei G, Snoeck R, De Clercq E, Balzarini J. Robins MJ, et al. Among authors: balzarini j. J Med Chem. 2007 Aug 9;50(16):3897-905. doi: 10.1021/jm070210n. Epub 2007 Jul 10. J Med Chem. 2007. PMID: 17622128

9

Organometallic nucleoside analogues with ferrocenyl linker groups: synthesis and cancer cell line studies.

Nguyen HV, Sallustrau A, Balzarini J, Bedford MR, Eden JC, Georgousi N, Hodges NJ, Kedge J, Mehellou Y, Tselepis C, Tucker JH. Nguyen HV, et al. Among authors: balzarini j. J Med Chem. 2014 Jul 10;57(13):5817-22. doi: 10.1021/jm500246h. Epub 2014 Jun 20. J Med Chem. 2014. PMID: 24905419 Free article.

10

Synthesis and biological evaluation of acyclic 3-[(2-hydroxyethoxy)methyl] analogues of antiviral furo- and pyrrolo[2,3-d]pyrimidine nucleosides.

Janeba Z, Balzarini J, Andrei G, Snoeck R, De Clercq E, Robins MJ. Janeba Z, et al. Among authors: balzarini j. J Med Chem. 2005 Jul 14;48(14):4690-6. doi: 10.1021/jm050291s. J Med Chem. 2005. PMID: 16000005

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