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Human Schwann cells exhibit long-term cell survival, are not tumorigenic and promote repair when transplanted into the contused spinal cord.
Bastidas J, Athauda G, De La Cruz G, Chan WM, Golshani R, Berrocal Y, Henao M, Lalwani A, Mannoji C, Assi M, Otero PA, Khan A, Marcillo AE, Norenberg M, Levi AD, Wood PM, Guest JD, Dietrich WD, Bartlett Bunge M, Pearse DD. Bastidas J, et al. Among authors: bartlett bunge m. Glia. 2017 Aug;65(8):1278-1301. doi: 10.1002/glia.23161. Epub 2017 May 22. Glia. 2017. PMID: 28543541
Safety of Autologous Human Schwann Cell Transplantation in Subacute Thoracic Spinal Cord Injury.
Anderson KD, Guest JD, Dietrich WD, Bartlett Bunge M, Curiel R, Dididze M, Green BA, Khan A, Pearse DD, Saraf-Lavi E, Widerström-Noga E, Wood P, Levi AD. Anderson KD, et al. Among authors: bartlett bunge m. J Neurotrauma. 2017 Nov 1;34(21):2950-2963. doi: 10.1089/neu.2016.4895. Epub 2017 Mar 21. J Neurotrauma. 2017. PMID: 28225648 Clinical Trial.