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A novel copper(II) complex identified as a potent drug against colorectal and breast cancer cells and as a poison inhibitor for human topoisomerase IIα.
Sandhaus S, Taylor R, Edwards T, Huddleston A, Wooten Y, Venkatraman R, Weber RT, González-Sarrías A, Martin PM, Cagle P, Tse-Dinh YC, Beebe SJ, Seeram N, Holder AA. Sandhaus S, et al. Among authors: beebe sj. Inorg Chem Commun. 2016 Feb;64:45-49. doi: 10.1016/j.inoche.2015.12.013. Inorg Chem Commun. 2016. PMID: 26752972 Free PMC article.
Synthesis, characterization, DNA binding, topoisomerase inhibition, and apoptosis induction studies of a novel cobalt(III) complex with a thiosemicarbazone ligand.
Beebe SJ, Celestine MJ, Bullock JL, Sandhaus S, Arca JF, Cropek DM, Ludvig TA, Foster SR, Clark JS, Beckford FA, Tano CM, Tonsel-White EA, Gurung RK, Stankavich CE, Tse-Dinh YC, Jarrett WL, Holder AA. Beebe SJ, et al. J Inorg Biochem. 2020 Feb;203:110907. doi: 10.1016/j.jinorgbio.2019.110907. Epub 2019 Nov 2. J Inorg Biochem. 2020. PMID: 31715377 Free PMC article.
105 results