Belyk KM - Search Results

1

Discovery of MK-4409, a Novel Oxazole FAAH Inhibitor for the Treatment of Inflammatory and Neuropathic Pain.

Chobanian HR, Guo Y, Liu P, Chioda MD, Fung S, Lanza TJ, Chang L, Bakshi RK, Dellureficio JP, Hong Q, McLaughlin M, Belyk KM, Krska SW, Makarewicz AK, Martel EJ, Leone JF, Frey L, Karanam B, Madeira M, Alvaro R, Shuman J, Salituro G, Terebetski JL, Jochnowitz N, Mistry S, McGowan E, Hajdu R, Rosenbach M, Abbadie C, Alexander JP, Shiao LL, Sullivan KM, Nargund RP, Wyvratt MJ, Lin LS, DeVita RJ. Chobanian HR, et al. Among authors: belyk km. ACS Med Chem Lett. 2014 Apr 10;5(6):717-21. doi: 10.1021/ml5001239. eCollection 2014 Jun 12. ACS Med Chem Lett. 2014. PMID: 24944750 Free PMC article.

2

Asymmetric hydrogenation of protected allylic amines.

Steinhuebel DP, Krska SW, Alorati A, Baxter JM, Belyk K, Bishop B, Palucki M, Sun Y, Davies IW. Steinhuebel DP, et al. Org Lett. 2010 Sep 17;12(18):4201-3. doi: 10.1021/ol101804e. Org Lett. 2010. PMID: 20735080

3

Synthesis of α-hydroxyacetophenones.

McLaughlin M, Belyk KM, Qian G, Reamer RA, Chen CY. McLaughlin M, et al. Among authors: belyk km. J Org Chem. 2012 Jun 1;77(11):5144-8. doi: 10.1021/jo3005556. Epub 2012 May 22. J Org Chem. 2012. PMID: 22568765

4

Enantioselective Rh(I)-Catalyzed Addition of Arylboronic Acids to Cyclic Ketimines.

Kong J, McLaughlin M, Belyk K, Mondschein R. Kong J, et al. Org Lett. 2015 Nov 20;17(22):5520-3. doi: 10.1021/acs.orglett.5b02032. Epub 2015 Nov 6. Org Lett. 2015. PMID: 26542775

5

Enantioselective Synthesis of 4'-Ethynyl-2-fluoro-2'-deoxyadenosine (EFdA) via Enzymatic Desymmetrization.

McLaughlin M, Kong J, Belyk KM, Chen B, Gibson AW, Keen SP, Lieberman DR, Milczek EM, Moore JC, Murray D, Peng F, Qi J, Reamer RA, Song ZJ, Tan L, Wang L, Williams MJ. McLaughlin M, et al. Among authors: belyk km. Org Lett. 2017 Feb 17;19(4):926-929. doi: 10.1021/acs.orglett.7b00091. Epub 2017 Feb 6. Org Lett. 2017. PMID: 28165251

6

Synthesis of bis-macrocyclic HCV protease inhibitor MK-6325 via intramolecular sp²-sp³ Suzuki-Miyaura coupling and ring closing metathesis.

Li H, Scott JP, Chen CY, Journet M, Belyk K, Balsells J, Kosjek B, Baxter CA, Stewart GW, Wise C, Alam M, Song ZJ, Tan L. Li H, et al. Org Lett. 2015 Mar 20;17(6):1533-6. doi: 10.1021/acs.orglett.5b00418. Epub 2015 Mar 10. Org Lett. 2015. PMID: 25754231

7

Synthesis of vaniprevir (MK-7009): lactamization to prepare a 20-membered [corrected] macrocycle.

Song ZJ, Tellers DM, Journet M, Kuethe JT, Lieberman D, Humphrey G, Zhang F, Peng Z, Waters MS, Zewge D, Nolting A, Zhao D, Reamer RA, Dormer PG, Belyk KM, Davies IW, Devine PN, Tschaen DM. Song ZJ, et al. Among authors: belyk km. J Org Chem. 2011 Oct 7;76(19):7804-15. doi: 10.1021/jo2011494. Epub 2011 Aug 31. J Org Chem. 2011. PMID: 21838271

8

Synthesis of the antifungal beta-1,3-glucan synthase inhibitor CANCIDAS (caspofungin acetate) from pneumocandin B0.

Leonard WR Jr, Belyk KM, Conlon DA, Bender DR, DiMichele LM, Liu J, Hughes DL. Leonard WR Jr, et al. Among authors: belyk km. J Org Chem. 2007 Mar 30;72(7):2335-43. doi: 10.1021/jo062008i. Epub 2007 Mar 8. J Org Chem. 2007. PMID: 17343416

9

Practical synthesis of 1,6-anhydro-2,4-dideoxy-beta-D-glycero-hexopyranos-3-ulose from levoglucosan.

Belyk KM, Leonard WR Jr, Bender DR, Hughes DL. Belyk KM, et al. J Org Chem. 2000 Apr 21;65(8):2588-90. doi: 10.1021/jo991719w. J Org Chem. 2000. PMID: 10789480 No abstract available.

10

Determination of the relative and absolute configuration of the dimethylmyristoyl side chain of pneumocandin B0 by asymmetric synthesis.

Leonard WR Jr, Belyk KM, Bender DR, Conlon DA, Hughes DL, Reider PJ. Leonard WR Jr, et al. Among authors: belyk km. Org Lett. 2002 Nov 28;4(24):4201-4. doi: 10.1021/ol0261940. Org Lett. 2002. PMID: 12443058

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