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Mutant copper-zinc superoxide dismutase (SOD1) induces protein secretion pathway alterations and exosome release in astrocytes: implications for disease spreading and motor neuron pathology in amyotrophic lateral sclerosis.
Basso M, Pozzi S, Tortarolo M, Fiordaliso F, Bisighini C, Pasetto L, Spaltro G, Lidonnici D, Gensano F, Battaglia E, Bendotti C, Bonetto V. Basso M, et al. Among authors: bendotti c. J Biol Chem. 2013 May 31;288(22):15699-711. doi: 10.1074/jbc.M112.425066. Epub 2013 Apr 16. J Biol Chem. 2013. PMID: 23592792 Free PMC article.
Lack of TNF-alpha receptor type 2 protects motor neurons in a cellular model of amyotrophic lateral sclerosis and in mutant SOD1 mice but does not affect disease progression.
Tortarolo M, Vallarola A, Lidonnici D, Battaglia E, Gensano F, Spaltro G, Fiordaliso F, Corbelli A, Garetto S, Martini E, Pasetto L, Kallikourdis M, Bonetto V, Bendotti C. Tortarolo M, et al. Among authors: bendotti c. J Neurochem. 2015 Oct;135(1):109-24. doi: 10.1111/jnc.13154. Epub 2015 Jun 4. J Neurochem. 2015. PMID: 25940956 Free article.
Glutamate AMPA receptors change in motor neurons of SOD1G93A transgenic mice and their inhibition by a noncompetitive antagonist ameliorates the progression of amytrophic lateral sclerosis-like disease.
Tortarolo M, Grignaschi G, Calvaresi N, Zennaro E, Spaltro G, Colovic M, Fracasso C, Guiso G, Elger B, Schneider H, Seilheimer B, Caccia S, Bendotti C. Tortarolo M, et al. Among authors: bendotti c. J Neurosci Res. 2006 Jan;83(1):134-46. doi: 10.1002/jnr.20715. J Neurosci Res. 2006. PMID: 16323214
Characterization of detergent-insoluble proteins in ALS indicates a causal link between nitrative stress and aggregation in pathogenesis.
Basso M, Samengo G, Nardo G, Massignan T, D'Alessandro G, Tartari S, Cantoni L, Marino M, Cheroni C, De Biasi S, Giordana MT, Strong MJ, Estevez AG, Salmona M, Bendotti C, Bonetto V. Basso M, et al. Among authors: bendotti c. PLoS One. 2009 Dec 2;4(12):e8130. doi: 10.1371/journal.pone.0008130. PLoS One. 2009. PMID: 19956584 Free PMC article.
193 results