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Monocarboxylate transporter MCT1 is a target for immunosuppression.
Murray CM, Hutchinson R, Bantick JR, Belfield GP, Benjamin AD, Brazma D, Bundick RV, Cook ID, Craggs RI, Edwards S, Evans LR, Harrison R, Holness E, Jackson AP, Jackson CG, Kingston LP, Perry MW, Ross AR, Rugman PA, Sidhu SS, Sullivan M, Taylor-Fishwick DA, Walker PC, Whitehead YM, Wilkinson DJ, Wright A, Donald DK. Murray CM, et al. Among authors: benjamin ad. Nat Chem Biol. 2005 Dec;1(7):371-6. doi: 10.1038/nchembio744. Nat Chem Biol. 2005. PMID: 16370372
Biological characterization of a novel class of toll-like receptor 7 agonists designed to have reduced systemic activity.
Biffen M, Matsui H, Edwards S, Leishman AJ, Eiho K, Holness E, Satterthwaite G, Doyle I, Wada H, Fraser NJ, Hawkins SL, Aoki M, Tomizawa H, Benjamin AD, Takaku H, McInally T, Murray CM. Biffen M, et al. Among authors: benjamin ad. Br J Pharmacol. 2012 May;166(2):573-86. doi: 10.1111/j.1476-5381.2011.01790.x. Br J Pharmacol. 2012. PMID: 22122192 Free PMC article.
Pre-clinical pharmacology of AZD3965, a selective inhibitor of MCT1: DLBCL, NHL and Burkitt's lymphoma anti-tumor activity.
Curtis NJ, Mooney L, Hopcroft L, Michopoulos F, Whalley N, Zhong H, Murray C, Logie A, Revill M, Byth KF, Benjamin AD, Firth MA, Green S, Smith PD, Critchlow SE. Curtis NJ, et al. Among authors: benjamin ad. Oncotarget. 2017 May 25;8(41):69219-69236. doi: 10.18632/oncotarget.18215. eCollection 2017 Sep 19. Oncotarget. 2017. PMID: 29050199 Free PMC article.
Renal Safety Pharmacology in Drug Discovery and Development.
Benjamin A, Nogueira da Costa A, Delaunois A, Rosseels ML, Valentin JP. Benjamin A, et al. Handb Exp Pharmacol. 2015;229:323-52. doi: 10.1007/978-3-662-46943-9_13. Handb Exp Pharmacol. 2015. PMID: 26091646 Review.
A multi-site comparison of in vivo safety pharmacology studies conducted to support ICH S7A & B regulatory submissions.
Ewart L, Milne A, Adkins D, Benjamin A, Bialecki R, Chen Y, Ericsson AC, Gardner S, Grant C, Lengel D, Lindgren S, Lowing S, Marks L, Moors J, Oldman K, Pietras M, Prior H, Punton J, Redfern WS, Salmond R, Skinner M, Some M, Stanton A, Swedberg M, Finch J, Valentin JP. Ewart L, et al. J Pharmacol Toxicol Methods. 2013 Jul-Aug;68(1):30-43. doi: 10.1016/j.vascn.2013.04.008. Epub 2013 May 9. J Pharmacol Toxicol Methods. 2013. PMID: 23665080
Studies in energy retrofit: institutional.
Benjamin AD. Benjamin AD. Heat Piping Air Cond. 1983 Mar;55(3):75-82. Heat Piping Air Cond. 1983. PMID: 10259014 No abstract available.
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