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Preclinical Pharmacology and Pharmacokinetics of Inhaled Hexadecyl-Treprostinil (C16TR), a Pulmonary Vasodilator Prodrug.
Corboz MR, Li Z, Malinin V, Plaunt AJ, Konicek DM, Leifer FG, Chen KJ, Laurent CE, Yin H, Biernat MC, Salvail D, Zhuang J, Xu F, Curran A, Perkins WR, Chapman RW. Corboz MR, et al. Among authors: biernat mc. J Pharmacol Exp Ther. 2017 Dec;363(3):348-357. doi: 10.1124/jpet.117.242099. Epub 2017 Sep 13. J Pharmacol Exp Ther. 2017. PMID: 28904003
Evaluation of the effects of RP5063, a novel, multimodal, serotonin receptor modulator, as single-agent therapy and co-administrated with sildenafil, bosentan, and treprostinil in a monocrotaline-induced pulmonary arterial hypertension rat model.
Bhat L, Hawkinson J, Cantillon M, Reddy DG, Bhat SR, Laurent CE, Bouchard A, Biernat M, Salvail D. Bhat L, et al. Eur J Pharmacol. 2018 May 15;827:159-166. doi: 10.1016/j.ejphar.2018.02.017. Epub 2018 Feb 14. Eur J Pharmacol. 2018. PMID: 29453947 Free article.