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Myristic acid induces proteomic and secretomic changes associated with steatosis, cytoskeleton remodeling, endoplasmic reticulum stress, protein turnover and exosome release in HepG2 cells.
Speziali G, Liesinger L, Gindlhuber J, Leopold C, Pucher B, Brandi J, Castagna A, Tomin T, Krenn P, Thallinger GG, Olivieri O, Martinelli N, Kratky D, Schittmayer M, Birner-Gruenberger R, Cecconi D. Speziali G, et al. J Proteomics. 2018 Jun 15;181:118-130. doi: 10.1016/j.jprot.2018.04.008. Epub 2018 Apr 12. J Proteomics. 2018. PMID: 29654920
Cholesteryl ester hydrolase activity is abolished in HSL-/- macrophages but unchanged in macrophages lacking KIAA1363.
Buchebner M, Pfeifer T, Rathke N, Chandak PG, Lass A, Schreiber R, Kratzer A, Zimmermann R, Sattler W, Koefeler H, Fröhlich E, Kostner GM, Birner-Gruenberger R, Chiang KP, Haemmerle G, Zechner R, Levak-Frank S, Cravatt B, Kratky D. Buchebner M, et al. J Lipid Res. 2010 Oct;51(10):2896-908. doi: 10.1194/jlr.M004259. Epub 2010 Jul 12. J Lipid Res. 2010. PMID: 20625037 Free PMC article.
Activity based subcellular resolution imaging of lipases.
Viertler M, Schittmayer M, Birner-Gruenberger R. Viertler M, et al. Bioorg Med Chem. 2012 Jan 15;20(2):628-32. doi: 10.1016/j.bmc.2011.04.018. Epub 2011 Apr 19. Bioorg Med Chem. 2012. PMID: 21570307
Lipolytic proteomics.
Schittmayer M, Birner-Gruenberger R. Schittmayer M, et al. Mass Spectrom Rev. 2012 Sep-Oct;31(5):570-82. doi: 10.1002/mas.20355. Epub 2012 Mar 5. Mass Spectrom Rev. 2012. PMID: 22392637
137 results