Bjørkøy G - Search Results

1

Structure-activity study leading to identification of a highly active thienopyrimidine based EGFR inhibitor.

Bugge S, Kaspersen SJ, Larsen S, Nonstad U, Bjørkøy G, Sundby E, Hoff BH. Bugge S, et al. Among authors: bjorkoy g. Eur J Med Chem. 2014 Mar 21;75:354-74. doi: 10.1016/j.ejmech.2014.01.042. Epub 2014 Jan 31. Eur J Med Chem. 2014. PMID: 24556149

2

Synthesis and in vitro EGFR (ErbB1) tyrosine kinase inhibitory activity of 4-N-substituted 6-aryl-7H-pyrrolo[2,3-d]pyrimidine-4-amines.

Kaspersen SJ, Sørum C, Willassen V, Fuglseth E, Kjøbli E, Bjørkøy G, Sundby E, Hoff BH. Kaspersen SJ, et al. Among authors: bjorkoy g. Eur J Med Chem. 2011 Dec;46(12):6002-14. doi: 10.1016/j.ejmech.2011.10.012. Epub 2011 Oct 15. Eur J Med Chem. 2011. PMID: 22018877

3

Identification of new 4-N-substituted 6-aryl-7H-pyrrolo[2,3-d]pyrimidine-4-amines as highly potent EGFR-TK inhibitors with Src-family activity.

Kaspersen SJ, Han J, Nørsett KG, Rydså L, Kjøbli E, Bugge S, Bjørkøy G, Sundby E, Hoff BH. Kaspersen SJ, et al. Among authors: bjorkoy g. Eur J Pharm Sci. 2014 Aug 1;59:69-82. doi: 10.1016/j.ejps.2014.04.011. Epub 2014 Apr 24. Eur J Pharm Sci. 2014. PMID: 24769040

4

Cancer cachexia associates with a systemic autophagy-inducing activity mimicked by cancer cell-derived IL-6 trans-signaling.

Pettersen K, Andersen S, Degen S, Tadini V, Grosjean J, Hatakeyama S, Tesfahun AN, Moestue S, Kim J, Nonstad U, Romundstad PR, Skorpen F, Sørhaug S, Amundsen T, Grønberg BH, Strasser F, Stephens N, Hoem D, Molven A, Kaasa S, Fearon K, Jacobi C, Bjørkøy G. Pettersen K, et al. Among authors: bjorkoy g. Sci Rep. 2017 May 17;7(1):2046. doi: 10.1038/s41598-017-02088-2. Sci Rep. 2017. PMID: 28515477 Free PMC article.

5

Autocrine activin A signalling in ovarian cancer cells regulates secretion of interleukin 6, autophagy, and cachexia.

Pettersen K, Andersen S, van der Veen A, Nonstad U, Hatakeyama S, Lambert C, Lach-Trifilieff E, Moestue S, Kim J, Grønberg BH, Schilb A, Jacobi C, Bjørkøy G. Pettersen K, et al. Among authors: bjorkoy g. J Cachexia Sarcopenia Muscle. 2020 Feb;11(1):195-207. doi: 10.1002/jcsm.12489. Epub 2019 Aug 21. J Cachexia Sarcopenia Muscle. 2020. PMID: 31436048 Free PMC article.

6

A highly selective purine-based inhibitor of CSF1R potently inhibits osteoclast differentiation.

Aarhus TI, Eickhoff J, Klebl B, Unger A, Boros J, Choidas A, Zischinsky ML, Wolowczyk C, Bjørkøy G, Sundby E, Hoff BH. Aarhus TI, et al. Among authors: bjorkoy g. Eur J Med Chem. 2023 Jul 5;255:115344. doi: 10.1016/j.ejmech.2023.115344. Epub 2023 Apr 28. Eur J Med Chem. 2023. PMID: 37141705 Free article.

7

Discovery of a new marker to identify myeloid cells associated with metastatic breast tumours.

Bokil AA, Le Boulvais Børkja M, Wolowczyk C, Lamsal A, Prestvik WS, Nonstad U, Pettersen K, Andersen SB, Bofin AM, Bjørkøy G, Hak S, Giambelluca MS. Bokil AA, et al. Among authors: bjorkoy g. Cancer Cell Int. 2023 Nov 18;23(1):279. doi: 10.1186/s12935-023-03136-w. Cancer Cell Int. 2023. PMID: 37980483 Free PMC article.

8

MRI reveals the in vivo cellular and vascular response to BEZ235 in ovarian cancer xenografts with different PI3-kinase pathway activity.

Cebulla J, Huuse EM, Pettersen K, van der Veen A, Kim E, Andersen S, Prestvik WS, Bofin AM, Pathak AP, Bjørkøy G, Bathen TF, Moestue SA. Cebulla J, et al. Among authors: bjorkoy g. Br J Cancer. 2015 Feb 3;112(3):504-13. doi: 10.1038/bjc.2014.628. Epub 2014 Dec 23. Br J Cancer. 2015. PMID: 25535727 Free PMC article.

9

Hydroxychloroquine potentiates carfilzomib toxicity towards myeloma cells.

Baranowska K, Misund K, Starheim KK, Holien T, Johansson I, Darvekar S, Buene G, Waage A, Bjørkøy G, Sundan A. Baranowska K, et al. Among authors: bjorkoy g. Oncotarget. 2016 Oct 25;7(43):70845-70856. doi: 10.18632/oncotarget.12226. Oncotarget. 2016. PMID: 27683126 Free PMC article.

10

Endocytosis of secreted carboxyl ester lipase in a syndrome of diabetes and pancreatic exocrine dysfunction.

Torsvik J, Johansson BB, Dalva M, Marie M, Fjeld K, Johansson S, Bjørkøy G, Saraste J, Njølstad PR, Molven A. Torsvik J, et al. Among authors: bjorkoy g. J Biol Chem. 2014 Oct 17;289(42):29097-111. doi: 10.1074/jbc.M114.574244. Epub 2014 Aug 25. J Biol Chem. 2014. PMID: 25160620 Free PMC article.

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