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Engineering an inhibitor-resistant human CSF1R variant for microglia replacement.
Chadarevian JP, Lombroso SI, Peet GC, Hasselmann J, Tu C, Marzan DE, Capocchi J, Purnell FS, Nemec KM, Lahian A, Escobar A, England W, Chaluvadi S, O'Brien CA, Yaqoob F, Aisenberg WH, Porras-Paniagua M, Bennett ML, Davtyan H, Spitale RC, Blurton-Jones M, Bennett FC. Chadarevian JP, et al. J Exp Med. 2023 Mar 6;220(3):e20220857. doi: 10.1084/jem.20220857. Epub 2022 Dec 30. J Exp Med. 2023. PMID: 36584406 Free PMC article.
Alteration of microglial metabolism and inflammatory profile contributes to neurotoxicity in a hiPSC-derived microglia model of frontotemporal dementia 3.
Haukedal H, Syshøj Lorenzen S, Winther Westi E, Corsi GI, Gadekar VP, McQuade A, Davtyan H, Doncheva NT, Schmid B, Chandrasekaran A, Seemann SE, Cirera S, Blurton-Jones M, Meyer M, Gorodkin J, Aldana BI, Freude K. Haukedal H, et al. Among authors: blurton jones m. Brain Behav Immun. 2023 Oct;113:353-373. doi: 10.1016/j.bbi.2023.07.024. Epub 2023 Aug 3. Brain Behav Immun. 2023. PMID: 37543250 Free article.
Caspase-mediated degeneration in Alzheimer's disease.
Cribbs DH, Poon WW, Rissman RA, Blurton-Jones M. Cribbs DH, et al. Am J Pathol. 2004 Aug;165(2):353-5. doi: 10.1016/S0002-9440(10)63302-0. Am J Pathol. 2004. PMID: 15277211 Free PMC article. Review. No abstract available.
Inflammatory changes parallel the early stages of Alzheimer disease.
Parachikova A, Agadjanyan MG, Cribbs DH, Blurton-Jones M, Perreau V, Rogers J, Beach TG, Cotman CW. Parachikova A, et al. Neurobiol Aging. 2007 Dec;28(12):1821-33. doi: 10.1016/j.neurobiolaging.2006.08.014. Epub 2006 Oct 18. Neurobiol Aging. 2007. PMID: 17052803 Free PMC article.
Pathways by which Abeta facilitates tau pathology.
Blurton-Jones M, Laferla FM. Blurton-Jones M, et al. Curr Alzheimer Res. 2006 Dec;3(5):437-48. doi: 10.2174/156720506779025242. Curr Alzheimer Res. 2006. PMID: 17168643 Review.
94 results