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Antibodies targeting the shared cytokine receptor IL-1 receptor accessory protein invoke distinct mechanisms to block all cytokine signaling.
Fields JK, Gyllenbäck EJ, Bogacz M, Obi J, Birkedal GS, Sjöström K, Maravillas K, Grönberg C, Rattik S, Kihn K, Flowers M, Smith AK, Hansen N, Fioretos T, Huyhn C, Liberg D, Deredge D, Sundberg EJ. Fields JK, et al. Among authors: bogacz m. Cell Rep. 2024 Apr 11:114099. doi: 10.1016/j.celrep.2024.114099. Online ahead of print. Cell Rep. 2024. PMID: 38636519 Free article.
Influence of amino acid size at the P3 position of N-Cbz-tripeptide Michael acceptors targeting falcipain-2 and rhodesain for the treatment of malaria and human african trypanosomiasis.
Previti S, Ettari R, Di Chio C, Legac J, Bogacz M, Zimmer C, Schirmeister T, Rosenthal PJ, Zappalà M. Previti S, et al. Among authors: bogacz m. Bioorg Chem. 2023 Aug;137:106587. doi: 10.1016/j.bioorg.2023.106587. Epub 2023 May 4. Bioorg Chem. 2023. PMID: 37163812 Free article.
Development of Urea-Bond-Containing Michael Acceptors as Antitrypanosomal Agents Targeting Rhodesain.
Previti S, Ettari R, Calcaterra E, Di Chio C, Ravichandran R, Zimmer C, Hammerschmidt S, Wagner A, Bogacz M, Cosconati S, Schirmeister T, Zappalà M. Previti S, et al. Among authors: bogacz m. ACS Med Chem Lett. 2022 Jun 30;13(7):1083-1090. doi: 10.1021/acsmedchemlett.2c00084. eCollection 2022 Jul 14. ACS Med Chem Lett. 2022. PMID: 35859868 Free PMC article.
23 results