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A Salmonella nanoparticle mimic overcomes multidrug resistance in tumours.
Mercado-Lubo R, Zhang Y, Zhao L, Rossi K, Wu X, Zou Y, Castillo A, Leonard J, Bortell R, Greiner DL, Shultz LD, Han G, McCormick BA. Mercado-Lubo R, et al. Among authors: bortell r. Nat Commun. 2016 Jul 25;7:12225. doi: 10.1038/ncomms12225. Nat Commun. 2016. PMID: 27452236 Free PMC article.
Viral infection of engrafted human islets leads to diabetes.
Gallagher GR, Brehm MA, Finberg RW, Barton BA, Shultz LD, Greiner DL, Bortell R, Wang JP. Gallagher GR, et al. Among authors: bortell r. Diabetes. 2015 Apr;64(4):1358-69. doi: 10.2337/db14-1020. Epub 2014 Nov 12. Diabetes. 2015. PMID: 25392246 Free PMC article.
Improved function and proliferation of adult human beta cells engrafted in diabetic immunodeficient NOD-scid IL2rγ(null) mice treated with alogliptin.
Jurczyk A, Diiorio P, Brostowin D, Leehy L, Yang C, Urano F, Harlan DM, Shultz LD, Greiner DL, Bortell R. Jurczyk A, et al. Among authors: bortell r. Diabetes Metab Syndr Obes. 2013 Dec 13;6:493-9. doi: 10.2147/DMSO.S53154. eCollection 2013. Diabetes Metab Syndr Obes. 2013. PMID: 24376359 Free PMC article.
Lixisenatide accelerates restoration of normoglycemia and improves human beta-cell function and survival in diabetic immunodeficient NOD-scid IL-2rg(null) RIP-DTR mice engrafted with human islets.
Yang C, Loehn M, Jurczyk A, Przewozniak N, Leehy L, Herrera PL, Shultz LD, Greiner DL, Harlan DM, Bortell R. Yang C, et al. Among authors: bortell r. Diabetes Metab Syndr Obes. 2015 Aug 20;8:387-98. doi: 10.2147/DMSO.S87253. eCollection 2015. Diabetes Metab Syndr Obes. 2015. PMID: 26316789 Free PMC article.
Genetic ablation of lymphocytes and cytokine signaling in nonobese diabetic mice prevents diet-induced obesity and insulin resistance.
Friedline RH, Ko HJ, Jung DY, Lee Y, Bortell R, Dagdeviren S, Patel PR, Hu X, Inashima K, Kearns C, Tsitsilianos N, Shafiq U, Shultz LD, Lee KW, Greiner DL, Kim JK. Friedline RH, et al. Among authors: bortell r. FASEB J. 2016 Mar;30(3):1328-38. doi: 10.1096/fj.15-280610. Epub 2015 Dec 7. FASEB J. 2016. PMID: 26644351 Free PMC article.
Beyond the brain: disrupted in schizophrenia 1 regulates pancreatic β-cell function via glycogen synthase kinase-3β.
Jurczyk A, Nowosielska A, Przewozniak N, Aryee KE, DiIorio P, Blodgett D, Yang C, Campbell-Thompson M, Atkinson M, Shultz L, Rittenhouse A, Harlan D, Greiner D, Bortell R. Jurczyk A, et al. Among authors: bortell r. FASEB J. 2016 Feb;30(2):983-93. doi: 10.1096/fj.15-279810. Epub 2015 Nov 6. FASEB J. 2016. PMID: 26546129 Free PMC article.
84 results