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Page 1
Resveratrol improves health and survival of mice on a high-calorie diet.
Baur JA, Pearson KJ, Price NL, Jamieson HA, Lerin C, Kalra A, Prabhu VV, Allard JS, Lopez-Lluch G, Lewis K, Pistell PJ, Poosala S, Becker KG, Boss O, Gwinn D, Wang M, Ramaswamy S, Fishbein KW, Spencer RG, Lakatta EG, Le Couteur D, Shaw RJ, Navas P, Puigserver P, Ingram DK, de Cabo R, Sinclair DA. Baur JA, et al. Among authors: boss o. Nature. 2006 Nov 16;444(7117):337-42. doi: 10.1038/nature05354. Epub 2006 Nov 1. Nature. 2006. PMID: 17086191 Free PMC article.
Small molecule activators of SIRT1 as therapeutics for the treatment of type 2 diabetes.
Milne JC, Lambert PD, Schenk S, Carney DP, Smith JJ, Gagne DJ, Jin L, Boss O, Perni RB, Vu CB, Bemis JE, Xie R, Disch JS, Ng PY, Nunes JJ, Lynch AV, Yang H, Galonek H, Israelian K, Choy W, Iffland A, Lavu S, Medvedik O, Sinclair DA, Olefsky JM, Jirousek MR, Elliott PJ, Westphal CH. Milne JC, et al. Among authors: boss o. Nature. 2007 Nov 29;450(7170):712-6. doi: 10.1038/nature06261. Nature. 2007. PMID: 18046409 Free PMC article.
Conserved role of SIRT1 orthologs in fasting-dependent inhibition of the lipid/cholesterol regulator SREBP.
Walker AK, Yang F, Jiang K, Ji JY, Watts JL, Purushotham A, Boss O, Hirsch ML, Ribich S, Smith JJ, Israelian K, Westphal CH, Rodgers JT, Shioda T, Elson SL, Mulligan P, Najafi-Shoushtari H, Black JC, Thakur JK, Kadyk LC, Whetstine JR, Mostoslavsky R, Puigserver P, Li X, Dyson NJ, Hart AC, Näär AM. Walker AK, et al. Among authors: boss o. Genes Dev. 2010 Jul 1;24(13):1403-17. doi: 10.1101/gad.1901210. Genes Dev. 2010. PMID: 20595232 Free PMC article.
Targeting PGC-1 alpha to control energy homeostasis.
Wu Z, Boss O. Wu Z, et al. Among authors: boss o. Expert Opin Ther Targets. 2007 Oct;11(10):1329-38. doi: 10.1517/14728222.11.10.1329. Expert Opin Ther Targets. 2007. PMID: 17907962 Review.
Divergence of melanocortin pathways in the control of food intake and energy expenditure.
Balthasar N, Dalgaard LT, Lee CE, Yu J, Funahashi H, Williams T, Ferreira M, Tang V, McGovern RA, Kenny CD, Christiansen LM, Edelstein E, Choi B, Boss O, Aschkenasi C, Zhang CY, Mountjoy K, Kishi T, Elmquist JK, Lowell BB. Balthasar N, et al. Among authors: boss o. Cell. 2005 Nov 4;123(3):493-505. doi: 10.1016/j.cell.2005.08.035. Cell. 2005. PMID: 16269339 Free article.
Increased energy expenditure, decreased adiposity, and tissue-specific insulin sensitivity in protein-tyrosine phosphatase 1B-deficient mice.
Klaman LD, Boss O, Peroni OD, Kim JK, Martino JL, Zabolotny JM, Moghal N, Lubkin M, Kim YB, Sharpe AH, Stricker-Krongrad A, Shulman GI, Neel BG, Kahn BB. Klaman LD, et al. Among authors: boss o. Mol Cell Biol. 2000 Aug;20(15):5479-89. doi: 10.1128/MCB.20.15.5479-5489.2000. Mol Cell Biol. 2000. PMID: 10891488 Free PMC article.
53 results