Bowman GD - Search Results

1

Missense variants in the chromatin remodeler CHD1 are associated with neurodevelopmental disability.

Pilarowski GO, Vernon HJ, Applegate CD, Boukas L, Cho MT, Gurnett CA, Benke PJ, Beaver E, Heeley JM, Medne L, Krantz ID, Azage M, Niyazov D, Henderson LB, Wentzensen IM, Baskin B, Sacoto MJG, Bowman GD, Bjornsson HT. Pilarowski GO, et al. Among authors: bowman gd. J Med Genet. 2018 Aug;55(8):561-566. doi: 10.1136/jmedgenet-2017-104759. Epub 2017 Sep 2. J Med Genet. 2018. PMID: 28866611 Free PMC article.

2

The chromodomains of the Chd1 chromatin remodeler regulate DNA access to the ATPase motor.

Hauk G, McKnight JN, Nodelman IM, Bowman GD. Hauk G, et al. Among authors: bowman gd. Mol Cell. 2010 Sep 10;39(5):711-23. doi: 10.1016/j.molcel.2010.08.012. Mol Cell. 2010. PMID: 20832723 Free PMC article.

3

Extranucleosomal DNA binding directs nucleosome sliding by Chd1.

McKnight JN, Jenkins KR, Nodelman IM, Escobar T, Bowman GD. McKnight JN, et al. Among authors: bowman gd. Mol Cell Biol. 2011 Dec;31(23):4746-59. doi: 10.1128/MCB.05735-11. Epub 2011 Oct 3. Mol Cell Biol. 2011. PMID: 21969605 Free PMC article.

4

Crystal structure of the chromodomain helicase DNA-binding protein 1 (Chd1) DNA-binding domain in complex with DNA.

Sharma A, Jenkins KR, Héroux A, Bowman GD. Sharma A, et al. Among authors: bowman gd. J Biol Chem. 2011 Dec 9;286(49):42099-42104. doi: 10.1074/jbc.C111.294462. Epub 2011 Oct 27. J Biol Chem. 2011. PMID: 22033927 Free PMC article.

5

Decoupling nucleosome recognition from DNA binding dramatically alters the properties of the Chd1 chromatin remodeler.

Patel A, Chakravarthy S, Morrone S, Nodelman IM, McKnight JN, Bowman GD. Patel A, et al. Among authors: bowman gd. Nucleic Acids Res. 2013 Feb 1;41(3):1637-48. doi: 10.1093/nar/gks1440. Epub 2012 Dec 28. Nucleic Acids Res. 2013. PMID: 23275572 Free PMC article.

6

Nucleosome sliding by Chd1 does not require rigid coupling between DNA-binding and ATPase domains.

Nodelman IM, Bowman GD. Nodelman IM, et al. Among authors: bowman gd. EMBO Rep. 2013 Dec;14(12):1098-103. doi: 10.1038/embor.2013.158. Epub 2013 Oct 15. EMBO Rep. 2013. PMID: 24126763 Free PMC article.

7

Sequence-targeted nucleosome sliding in vivo by a hybrid Chd1 chromatin remodeler.

McKnight JN, Tsukiyama T, Bowman GD. McKnight JN, et al. Among authors: bowman gd. Genome Res. 2016 May;26(5):693-704. doi: 10.1101/gr.199919.115. Epub 2016 Mar 18. Genome Res. 2016. PMID: 26993344 Free PMC article.

8

The Chd1 chromatin remodeler can sense both entry and exit sides of the nucleosome.

Nodelman IM, Horvath KC, Levendosky RF, Winger J, Ren R, Patel A, Li M, Wang MD, Roberts E, Bowman GD. Nodelman IM, et al. Among authors: bowman gd. Nucleic Acids Res. 2016 Sep 19;44(16):7580-91. doi: 10.1093/nar/gkw406. Epub 2016 May 12. Nucleic Acids Res. 2016. PMID: 27174939 Free PMC article.

9

The Chd1 chromatin remodeler shifts hexasomes unidirectionally.

Levendosky RF, Sabantsev A, Deindl S, Bowman GD. Levendosky RF, et al. Among authors: bowman gd. Elife. 2016 Dec 29;5:e21356. doi: 10.7554/eLife.21356. Elife. 2016. PMID: 28032848 Free PMC article.

10

Interdomain Communication of the Chd1 Chromatin Remodeler across the DNA Gyres of the Nucleosome.

Nodelman IM, Bleichert F, Patel A, Ren R, Horvath KC, Berger JM, Bowman GD. Nodelman IM, et al. Among authors: bowman gd. Mol Cell. 2017 Feb 2;65(3):447-459.e6. doi: 10.1016/j.molcel.2016.12.011. Epub 2017 Jan 19. Mol Cell. 2017. PMID: 28111016 Free PMC article.

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