Brady SF - Search Results

1

DNA glycosylases provide antiviral defence in prokaryotes.

Hossain AA, Pigli YZ, Baca CF, Heissel S, Thomas A, Libis VK, Burian J, Chappie JS, Brady SF, Rice PA, Marraffini LA. Hossain AA, et al. Among authors: brady sf. Nature. 2024 Apr 17. doi: 10.1038/s41586-024-07329-9. Online ahead of print. Nature. 2024. PMID: 38632404

2

Identification of an Optimized Clinical Development Candidate from Cilagicin, an Antibiotic That Evades Resistance by Dual Polyprenyl Phosphate Binding.

Rosenzweig A, Spotton K, Bhattacharjee A, Morales-Amador A, Brady SF. Rosenzweig A, et al. Among authors: brady sf. ACS Infect Dis. 2024 Apr 16. doi: 10.1021/acsinfecdis.4c00018. Online ahead of print. ACS Infect Dis. 2024. PMID: 38626307

3

Tapcin, an In Vivo Active Dual Topoisomerase I/II Inhibitor Discovered by Synthetic Bioinformatic Natural Product (Syn-BNP)-Coupled Metagenomics.

Wang Z, Kasper A, Takahashi M, Morales Amador A, Bhattacharjee A, Kan J, Hernandez Y, Ternei M, Brady SF. Wang Z, et al. Among authors: brady sf. Angew Chem Int Ed Engl. 2024 Apr 22;63(17):e202317187. doi: 10.1002/anie.202317187. Epub 2024 Mar 20. Angew Chem Int Ed Engl. 2024. PMID: 38231130

4

Author Correction: Bacterial cGAS senses a viral RNA to initiate immunity.

Banh DV, Roberts CG, Morales-Amador A, Berryhill BA, Chaudhry W, Levin BR, Brady SF, Marraffini LA. Banh DV, et al. Among authors: brady sf. Nature. 2024 Jan;625(7993):E3. doi: 10.1038/s41586-023-06929-1. Nature. 2024. PMID: 38052939 Free PMC article. No abstract available.

5

Bacterial cGAS senses a viral RNA to initiate immunity.

Banh DV, Roberts CG, Morales-Amador A, Berryhill BA, Chaudhry W, Levin BR, Brady SF, Marraffini LA. Banh DV, et al. Among authors: brady sf. Nature. 2023 Nov;623(7989):1001-1008. doi: 10.1038/s41586-023-06743-9. Epub 2023 Nov 15. Nature. 2023. PMID: 37968393 Free PMC article.

6

A Family of Antibiotics That Evades Resistance by Binding Polyprenyl Phosphates.

Rosenzweig AF, Wang Z, Morales-Amador A, Spotton K, Brady SF. Rosenzweig AF, et al. Among authors: brady sf. ACS Infect Dis. 2023 Dec 8;9(12):2394-2400. doi: 10.1021/acsinfecdis.3c00475. Epub 2023 Nov 8. ACS Infect Dis. 2023. PMID: 37937847 Free PMC article.

7

Present and future outlooks on environmental DNA-based methods for antibiotic discovery.

Rosenzweig AF, Burian J, Brady SF. Rosenzweig AF, et al. Among authors: brady sf. Curr Opin Microbiol. 2023 Oct;75:102335. doi: 10.1016/j.mib.2023.102335. Epub 2023 Jun 14. Curr Opin Microbiol. 2023. PMID: 37327680 Review.

8

High-throughput retrieval of target sequences from complex clone libraries using CRISPRi.

Burian J, Libis VK, Hernandez YA, Guerrero-Porras L, Ternei MA, Brady SF. Burian J, et al. Among authors: brady sf. Nat Biotechnol. 2023 May;41(5):626-630. doi: 10.1038/s41587-022-01531-8. Epub 2022 Nov 21. Nat Biotechnol. 2023. PMID: 36411313 Free PMC article.

9

Multiplexed mobilization and expression of biosynthetic gene clusters.

Libis V, MacIntyre LW, Mehmood R, Guerrero L, Ternei MA, Antonovsky N, Burian J, Wang Z, Brady SF. Libis V, et al. Among authors: brady sf. Nat Commun. 2022 Sep 6;13(1):5256. doi: 10.1038/s41467-022-32858-0. Nat Commun. 2022. PMID: 36068239 Free PMC article.

10

Discovery of Paenibacillaceae Family Gram-Negative-Active Cationic Lipopeptide Antibiotics Using Evolution-Guided Chemical Synthesis.

Wang Z, Koirala B, Hernandez Y, Brady SF. Wang Z, et al. Among authors: brady sf. Org Lett. 2022 Jul 15;24(27):4943-4948. doi: 10.1021/acs.orglett.2c01879. Epub 2022 Jul 1. Org Lett. 2022. PMID: 35776528 Free PMC article.

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