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Analysis of the caudate nucleus transcriptome in individuals with schizophrenia highlights effects of antipsychotics and new risk genes.
Benjamin KJM, Chen Q, Jaffe AE, Stolz JM, Collado-Torres L, Huuki-Myers LA, Burke EE, Arora R, Feltrin AS, Barbosa AR, Radulescu E, Pergola G, Shin JH, Ulrich WS, Deep-Soboslay A, Tao R; BrainSeq Consortium; Hyde TM, Kleinman JE, Erwin JA, Weinberger DR, Paquola ACM. Benjamin KJM, et al. Nat Neurosci. 2022 Nov;25(11):1559-1568. doi: 10.1038/s41593-022-01182-7. Epub 2022 Nov 1. Nat Neurosci. 2022. PMID: 36319771 Free PMC article.
Developmental and genetic regulation of the human cortex transcriptome illuminate schizophrenia pathogenesis.
Jaffe AE, Straub RE, Shin JH, Tao R, Gao Y, Collado-Torres L, Kam-Thong T, Xi HS, Quan J, Chen Q, Colantuoni C, Ulrich WS, Maher BJ, Deep-Soboslay A; BrainSeq Consortium; Cross AJ, Brandon NJ, Leek JT, Hyde TM, Kleinman JE, Weinberger DR. Jaffe AE, et al. Nat Neurosci. 2018 Aug;21(8):1117-1125. doi: 10.1038/s41593-018-0197-y. Epub 2018 Jul 26. Nat Neurosci. 2018. PMID: 30050107 Free PMC article.
Investigating the neuroimmunogenic architecture of schizophrenia.
Birnbaum R, Jaffe AE, Chen Q, Shin JH; BrainSeq Consortium; Kleinman JE, Hyde TM, Weinberger DR. Birnbaum R, et al. Mol Psychiatry. 2018 May;23(5):1251-1260. doi: 10.1038/mp.2017.89. Epub 2017 May 9. Mol Psychiatry. 2018. PMID: 28485405
Regional Heterogeneity in Gene Expression, Regulation, and Coherence in the Frontal Cortex and Hippocampus across Development and Schizophrenia.
Collado-Torres L, Burke EE, Peterson A, Shin J, Straub RE, Rajpurohit A, Semick SA, Ulrich WS; BrainSeq Consortium; Price AJ, Valencia C, Tao R, Deep-Soboslay A, Hyde TM, Kleinman JE, Weinberger DR, Jaffe AE. Collado-Torres L, et al. Neuron. 2019 Jul 17;103(2):203-216.e8. doi: 10.1016/j.neuron.2019.05.013. Epub 2019 Jun 4. Neuron. 2019. PMID: 31174959 Free PMC article.