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Page 1
Intrinsic efficacy of antipsychotics at human D2, D3, and D4 dopamine receptors: identification of the clozapine metabolite N-desmethylclozapine as a D2/D3 partial agonist.
Burstein ES, Ma J, Wong S, Gao Y, Pham E, Knapp AE, Nash NR, Olsson R, Davis RE, Hacksell U, Weiner DM, Brann MR. Burstein ES, et al. Among authors: brann mr. J Pharmacol Exp Ther. 2005 Dec;315(3):1278-87. doi: 10.1124/jpet.105.092155. Epub 2005 Aug 31. J Pharmacol Exp Ther. 2005. PMID: 16135699
Pharmacological characterization of AC-90179 [2-(4-methoxyphenyl)-N-(4-methyl-benzyl)-N-(1-methyl-piperidin-4-yl)-acetamide hydrochloride]: a selective serotonin 2A receptor inverse agonist.
Vanover KE, Harvey SC, Son T, Bradley SR, Kold H, Makhay M, Veinbergs I, Spalding TA, Weiner DM, Andersson CM, Tolf BR, Brann MR, Hacksell U, Davis RE. Vanover KE, et al. Among authors: brann mr. J Pharmacol Exp Ther. 2004 Sep;310(3):943-51. doi: 10.1124/jpet.104.066688. Epub 2004 Apr 21. J Pharmacol Exp Ther. 2004. PMID: 15102927
Pharmacological and behavioral profile of N-(4-fluorophenylmethyl)-N-(1-methylpiperidin-4-yl)-N'-(4-(2-methylpropyloxy)phenylmethyl) carbamide (2R,3R)-dihydroxybutanedioate (2:1) (ACP-103), a novel 5-hydroxytryptamine(2A) receptor inverse agonist.
Vanover KE, Weiner DM, Makhay M, Veinbergs I, Gardell LR, Lameh J, Del Tredici AL, Piu F, Schiffer HH, Ott TR, Burstein ES, Uldam AK, Thygesen MB, Schlienger N, Andersson CM, Son TY, Harvey SC, Powell SB, Geyer MA, Tolf BR, Brann MR, Davis RE. Vanover KE, et al. Among authors: brann mr. J Pharmacol Exp Ther. 2006 May;317(2):910-8. doi: 10.1124/jpet.105.097006. Epub 2006 Feb 9. J Pharmacol Exp Ther. 2006. PMID: 16469866
ACP-103, a 5-hydroxytryptamine 2A receptor inverse agonist, improves the antipsychotic efficacy and side-effect profile of haloperidol and risperidone in experimental models.
Gardell LR, Vanover KE, Pounds L, Johnson RW, Barido R, Anderson GT, Veinbergs I, Dyssegaard A, Brunmark P, Tabatabaei A, Davis RE, Brann MR, Hacksell U, Bonhaus DW. Gardell LR, et al. Among authors: brann mr. J Pharmacol Exp Ther. 2007 Aug;322(2):862-70. doi: 10.1124/jpet.107.121715. Epub 2007 May 22. J Pharmacol Exp Ther. 2007. PMID: 17519387
Identification of novel selective V2 receptor non-peptide agonists.
Del Tredici AL, Vanover KE, Knapp AE, Bertozzi SM, Nash NR, Burstein ES, Lameh J, Currier EA, Davis RE, Brann MR, Mohell N, Olsson R, Piu F. Del Tredici AL, et al. Among authors: brann mr. Biochem Pharmacol. 2008 Oct 30;76(9):1134-41. doi: 10.1016/j.bcp.2008.08.004. Epub 2008 Aug 12. Biochem Pharmacol. 2008. PMID: 18761325
5-hydroxytryptamine2A receptor inverse agonists as antipsychotics.
Weiner DM, Burstein ES, Nash N, Croston GE, Currier EA, Vanover KE, Harvey SC, Donohue E, Hansen HC, Andersson CM, Spalding TA, Gibson DF, Krebs-Thomson K, Powell SB, Geyer MA, Hacksell U, Brann MR. Weiner DM, et al. Among authors: brann mr. J Pharmacol Exp Ther. 2001 Oct;299(1):268-76. J Pharmacol Exp Ther. 2001. PMID: 11561089
The role of M1 muscarinic receptor agonism of N-desmethylclozapine in the unique clinical effects of clozapine.
Weiner DM, Meltzer HY, Veinbergs I, Donohue EM, Spalding TA, Smith TT, Mohell N, Harvey SC, Lameh J, Nash N, Vanover KE, Olsson R, Jayathilake K, Lee M, Levey AI, Hacksell U, Burstein ES, Davis RE, Brann MR. Weiner DM, et al. Among authors: brann mr. Psychopharmacology (Berl). 2004 Dec;177(1-2):207-16. doi: 10.1007/s00213-004-1940-5. Epub 2004 Jul 16. Psychopharmacology (Berl). 2004. PMID: 15258717
114 results