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Page 1
Identification of evolutionarily conserved genetic regulators of cellular aging.
Laschober GT, Ruli D, Hofer E, Muck C, Carmona-Gutierrez D, Ring J, Hutter E, Ruckenstuhl C, Micutkova L, Brunauer R, Jamnig A, Trimmel D, Herndler-Brandstetter D, Brunner S, Zenzmaier C, Sampson N, Breitenbach M, Fröhlich KU, Grubeck-Loebenstein B, Berger P, Wieser M, Grillari-Voglauer R, Thallinger GG, Grillari J, Trajanoski Z, Madeo F, Lepperdinger G, Jansen-Dürr P. Laschober GT, et al. Among authors: breitenbach m. Aging Cell. 2010 Dec;9(6):1084-97. doi: 10.1111/j.1474-9726.2010.00637.x. Epub 2010 Oct 28. Aging Cell. 2010. PMID: 20883526 Free PMC article.
miR-17, miR-19b, miR-20a, and miR-106a are down-regulated in human aging.
Hackl M, Brunner S, Fortschegger K, Schreiner C, Micutkova L, Mück C, Laschober GT, Lepperdinger G, Sampson N, Berger P, Herndler-Brandstetter D, Wieser M, Kühnel H, Strasser A, Rinnerthaler M, Breitenbach M, Mildner M, Eckhart L, Tschachler E, Trost A, Bauer JW, Papak C, Trajanoski Z, Scheideler M, Grillari-Voglauer R, Grubeck-Loebenstein B, Jansen-Dürr P, Grillari J. Hackl M, et al. Among authors: breitenbach m. Aging Cell. 2010 Apr;9(2):291-6. doi: 10.1111/j.1474-9726.2010.00549.x. Epub 2010 Jan 18. Aging Cell. 2010. PMID: 20089119 Free PMC article.
The mitochondrial ribosomal protein of the large subunit, Afo1p, determines cellular longevity through mitochondrial back-signaling via TOR1.
Heeren G, Rinnerthaler M, Laun P, von Seyerl P, Kössler S, Klinger H, Hager M, Bogengruber E, Jarolim S, Simon-Nobbe B, Schüller C, Carmona-Gutierrez D, Breitenbach-Koller L, Mück C, Jansen-Dürr P, Criollo A, Kroemer G, Madeo F, Breitenbach M. Heeren G, et al. Among authors: breitenbach m, breitenbach koller l. Aging (Albany NY). 2009 Jul 13;1(7):622-36. doi: 10.18632/aging.100065. Aging (Albany NY). 2009. PMID: 20157544 Free PMC article.
The use of genetically engineered model systems for research on human aging.
Lepperdinger G, Berger P, Breitenbach M, Frohlich KU, Grillari J, Grubeck-Loebenstein B, Madeo F, Minois N, Zwerschke W, Jansen-Durr P. Lepperdinger G, et al. Among authors: breitenbach m. Front Biosci. 2008 May 1;13:7022-31. doi: 10.2741/3207. Front Biosci. 2008. PMID: 18508713
Induction of autophagy by spermidine promotes longevity.
Eisenberg T, Knauer H, Schauer A, Büttner S, Ruckenstuhl C, Carmona-Gutierrez D, Ring J, Schroeder S, Magnes C, Antonacci L, Fussi H, Deszcz L, Hartl R, Schraml E, Criollo A, Megalou E, Weiskopf D, Laun P, Heeren G, Breitenbach M, Grubeck-Loebenstein B, Herker E, Fahrenkrog B, Fröhlich KU, Sinner F, Tavernarakis N, Minois N, Kroemer G, Madeo F. Eisenberg T, et al. Among authors: breitenbach m. Nat Cell Biol. 2009 Nov;11(11):1305-14. doi: 10.1038/ncb1975. Epub 2009 Oct 4. Nat Cell Biol. 2009. PMID: 19801973
A new dominant peroxiredoxin allele identified by whole-genome re-sequencing of random mutagenized yeast causes oxidant-resistance and premature aging.
Timmermann B, Jarolim S, Russmayer H, Kerick M, Michel S, Krüger A, Bluemlein K, Laun P, Grillari J, Lehrach H, Breitenbach M, Ralser M. Timmermann B, et al. Among authors: breitenbach m. Aging (Albany NY). 2010 Aug;2(8):475-86. doi: 10.18632/aging.100187. Aging (Albany NY). 2010. PMID: 20729566 Free PMC article.
A yeast BH3-only protein mediates the mitochondrial pathway of apoptosis.
Büttner S, Ruli D, Vögtle FN, Galluzzi L, Moitzi B, Eisenberg T, Kepp O, Habernig L, Carmona-Gutierrez D, Rockenfeller P, Laun P, Breitenbach M, Khoury C, Fröhlich KU, Rechberger G, Meisinger C, Kroemer G, Madeo F. Büttner S, et al. Among authors: breitenbach m. EMBO J. 2011 Jun 14;30(14):2779-92. doi: 10.1038/emboj.2011.197. EMBO J. 2011. PMID: 21673659 Free PMC article.
A comparison of the aging and apoptotic transcriptome of Saccharomyces cerevisiae.
Laun P, Ramachandran L, Jarolim S, Herker E, Liang P, Wang J, Weinberger M, Burhans DT, Suter B, Madeo F, Burhans WC, Breitenbach M. Laun P, et al. Among authors: breitenbach m. FEMS Yeast Res. 2005 Dec;5(12):1261-72. doi: 10.1016/j.femsyr.2005.07.006. Epub 2005 Aug 31. FEMS Yeast Res. 2005. PMID: 16168721
210 results