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The adaptor ASC has extracellular and 'prionoid' activities that propagate inflammation.
Franklin BS, Bossaller L, De Nardo D, Ratter JM, Stutz A, Engels G, Brenker C, Nordhoff M, Mirandola SR, Al-Amoudi A, Mangan MS, Zimmer S, Monks BG, Fricke M, Schmidt RE, Espevik T, Jones B, Jarnicki AG, Hansbro PM, Busto P, Marshak-Rothstein A, Hornemann S, Aguzzi A, Kastenmüller W, Latz E. Franklin BS, et al. Among authors: brenker c. Nat Immunol. 2014 Aug;15(8):727-37. doi: 10.1038/ni.2913. Epub 2014 Jun 22. Nat Immunol. 2014. PMID: 24952505 Free PMC article.
The CatSper channel: a polymodal chemosensor in human sperm.
Brenker C, Goodwin N, Weyand I, Kashikar ND, Naruse M, Krähling M, Müller A, Kaupp UB, Strünker T. Brenker C, et al. EMBO J. 2012 Apr 4;31(7):1654-65. doi: 10.1038/emboj.2012.30. Epub 2012 Feb 21. EMBO J. 2012. PMID: 22354039 Free PMC article.
The Ca2+-activated K+ current of human sperm is mediated by Slo3.
Brenker C, Zhou Y, Müller A, Echeverry FA, Trötschel C, Poetsch A, Xia XM, Bönigk W, Lingle CJ, Kaupp UB, Strünker T. Brenker C, et al. Elife. 2014 Mar 26;3:e01438. doi: 10.7554/eLife.01438. Elife. 2014. PMID: 24670955 Free PMC article.
Direct action of endocrine disrupting chemicals on human sperm.
Schiffer C, Müller A, Egeberg DL, Alvarez L, Brenker C, Rehfeld A, Frederiksen H, Wäschle B, Kaupp UB, Balbach M, Wachten D, Skakkebaek NE, Almstrup K, Strünker T. Schiffer C, et al. Among authors: brenker c. EMBO Rep. 2014 Jul;15(7):758-65. doi: 10.15252/embr.201438869. Epub 2014 May 12. EMBO Rep. 2014. PMID: 24820036 Free PMC article.
Sperm navigation along helical paths in 3D chemoattractant landscapes.
Jikeli JF, Alvarez L, Friedrich BM, Wilson LG, Pascal R, Colin R, Pichlo M, Rennhack A, Brenker C, Kaupp UB. Jikeli JF, et al. Among authors: brenker c. Nat Commun. 2015 Aug 17;6:7985. doi: 10.1038/ncomms8985. Nat Commun. 2015. PMID: 26278469 Free PMC article.
Action of steroids and plant triterpenoids on CatSper Ca2+ channels in human sperm.
Brenker C, Schiffer C, Wagner IV, Tüttelmann F, Röpke A, Rennhack A, Kaupp UB, Strünker T. Brenker C, et al. Proc Natl Acad Sci U S A. 2018 Jan 16;115(3):E344-E346. doi: 10.1073/pnas.1717929115. Epub 2018 Jan 5. Proc Natl Acad Sci U S A. 2018. PMID: 29305558 Free PMC article. No abstract available.
A novel cross-species inhibitor to study the function of CatSper Ca2+ channels in sperm.
Rennhack A, Schiffer C, Brenker C, Fridman D, Nitao ET, Cheng YM, Tamburrino L, Balbach M, Stölting G, Berger TK, Kierzek M, Alvarez L, Wachten D, Zeng XH, Baldi E, Publicover SJ, Kaupp UB, Strünker T. Rennhack A, et al. Among authors: brenker c. Br J Pharmacol. 2018 Aug;175(15):3144-3161. doi: 10.1111/bph.14355. Epub 2018 Jun 29. Br J Pharmacol. 2018. PMID: 29723408 Free PMC article.
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