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The heavy subunit of ferritin stimulates NLRP3 inflammasomes in hepatic stellate cells through ICAM-1 to drive hepatic inflammation.
Fernandez-Rojo MA, Pearen MA, Burgess AG, Ikonomopoulou MP, Hoang-Le D, Genz B, Saggiomo SL, Nawaratna SSK, Poli M, Reissmann R, Gobert GN, Deutsch U, Engelhardt B, Brooks AJ, Jones A, Arosio P, Ramm GA. Fernandez-Rojo MA, et al. Among authors: brooks aj. Sci Signal. 2024 Apr 2;17(830):eade4335. doi: 10.1126/scisignal.ade4335. Epub 2024 Apr 2. Sci Signal. 2024. PMID: 38564492
Author Correction: Discovery of an exosite on the SOCS2-SH2 domain that enhances SH2 binding to phosphorylated ligands.
Linossi EM, Li K, Veggiani G, Tan C, Dehkhoda F, Hockings C, Calleja DJ, Keating N, Feltham R, Brooks AJ, Li SS, Sidhu SS, Babon JJ, Kershaw NJ, Nicholson SE. Linossi EM, et al. Among authors: brooks aj. Nat Commun. 2023 Dec 1;14(1):7951. doi: 10.1038/s41467-023-42706-4. Nat Commun. 2023. PMID: 38040684 Free PMC article. No abstract available.
208 results