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Exome-wide association study of plasma lipids in >300,000 individuals.
Liu DJ, Peloso GM, Yu H, Butterworth AS, Wang X, Mahajan A, Saleheen D, Emdin C, Alam D, Alves AC, Amouyel P, Di Angelantonio E, Arveiler D, Assimes TL, Auer PL, Baber U, Ballantyne CM, Bang LE, Benn M, Bis JC, Boehnke M, Boerwinkle E, Bork-Jensen J, Bottinger EP, Brandslund I, Brown M, Busonero F, Caulfield MJ, Chambers JC, Chasman DI, Chen YE, Chen YI, Chowdhury R, Christensen C, Chu AY, Connell JM, Cucca F, Cupples LA, Damrauer SM, Davies G, Deary IJ, Dedoussis G, Denny JC, Dominiczak A, Dubé MP, Ebeling T, Eiriksdottir G, Esko T, Farmaki AE, Feitosa MF, Ferrario M, Ferrieres J, Ford I, Fornage M, Franks PW, Frayling TM, Frikke-Schmidt R, Fritsche LG, Frossard P, Fuster V, Ganesh SK, Gao W, Garcia ME, Gieger C, Giulianini F, Goodarzi MO, Grallert H, Grarup N, Groop L, Grove ML, Gudnason V, Hansen T, Harris TB, Hayward C, Hirschhorn JN, Holmen OL, Huffman J, Huo Y, Hveem K, Jabeen S, Jackson AU, Jakobsdottir J, Jarvelin MR, Jensen GB, Jørgensen ME, Jukema JW, Justesen JM, Kamstrup PR, Kanoni S, Karpe F, Kee F, Khera AV, Klarin D, Koistinen HA, Kooner JS, Kooperberg C, Kuulasmaa K, Kuusisto J, Laakso M, Lakka T, Langenberg C, Langsted A, Launer LJ, Lauritzen T, Liewald DCM… See abstract for full author list ➔ Liu DJ, et al. Among authors: brown m. Nat Genet. 2017 Dec;49(12):1758-1766. doi: 10.1038/ng.3977. Epub 2017 Oct 30. Nat Genet. 2017. PMID: 29083408 Free PMC article.
Genome-wide mapping of human loci for essential hypertension.
Caulfield M, Munroe P, Pembroke J, Samani N, Dominiczak A, Brown M, Benjamin N, Webster J, Ratcliffe P, O'Shea S, Papp J, Taylor E, Dobson R, Knight J, Newhouse S, Hooper J, Lee W, Brain N, Clayton D, Lathrop GM, Farrall M, Connell J; MRC British Genetics of Hypertension Study. Caulfield M, et al. Among authors: brown m. Lancet. 2003 Jun 21;361(9375):2118-23. doi: 10.1016/S0140-6736(03)13722-1. Lancet. 2003. PMID: 12826435
Haplotypes of the WNK1 gene associate with blood pressure variation in a severely hypertensive population from the British Genetics of Hypertension study.
Newhouse SJ, Wallace C, Dobson R, Mein C, Pembroke J, Farrall M, Clayton D, Brown M, Samani N, Dominiczak A, Connell JM, Webster J, Lathrop GM, Caulfield M, Munroe PB. Newhouse SJ, et al. Among authors: brown m. Hum Mol Genet. 2005 Jul 1;14(13):1805-14. doi: 10.1093/hmg/ddi187. Epub 2005 May 11. Hum Mol Genet. 2005. PMID: 15888480
Two-dimensional genome-scan identifies novel epistatic loci for essential hypertension.
Bell JT, Wallace C, Dobson R, Wiltshire S, Mein C, Pembroke J, Brown M, Clayton D, Samani N, Dominiczak A, Webster J, Lathrop GM, Connell J, Munroe P, Caulfield M, Farrall M. Bell JT, et al. Among authors: brown m. Hum Mol Genet. 2006 Apr 15;15(8):1365-74. doi: 10.1093/hmg/ddl058. Epub 2006 Mar 16. Hum Mol Genet. 2006. PMID: 16543358
Increased support for linkage of a novel locus on chromosome 5q13 for essential hypertension in the British Genetics of Hypertension Study.
Munroe PB, Wallace C, Xue MZ, Marçano AC, Dobson RJ, Onipinla AK, Burke B, Gungadoo J, Newhouse SJ, Pembroke J, Brown M, Dominiczak AF, Samani NJ, Lathrop M, Connell J, Webster J, Clayton D, Farrall M, Mein CA, Caulfield M; Medical Research Council British Genetics of Hypertension Study. Munroe PB, et al. Among authors: brown m. Hypertension. 2006 Jul;48(1):105-11. doi: 10.1161/01.HYP.0000228324.74255.f1. Epub 2006 Jun 5. Hypertension. 2006. PMID: 16754790
Linkage analysis using co-phenotypes in the BRIGHT study reveals novel potential susceptibility loci for hypertension.
Wallace C, Xue MZ, Newhouse SJ, Marcano AC, Onipinla AK, Burke B, Gungadoo J, Dobson RJ, Brown M, Connell JM, Dominiczak A, Lathrop GM, Webster J, Farrall M, Mein C, Samani NJ, Caulfield MJ, Clayton DG, Munroe PB. Wallace C, et al. Among authors: brown m. Am J Hum Genet. 2006 Aug;79(2):323-31. doi: 10.1086/506370. Epub 2006 Jun 19. Am J Hum Genet. 2006. PMID: 16826522 Free PMC article.
Polymorphic variation in the 11beta-hydroxylase gene associates with reduced 11-hydroxylase efficiency.
Barr M, MacKenzie SM, Friel EC, Holloway CD, Wilkinson DM, Brain NJ, Ingram MC, Fraser R, Brown M, Samani NJ, Caulfield M, Munroe PB, Farrall M, Webster J, Clayton D, Dominiczak AF, Connell JM, Davies E. Barr M, et al. Among authors: brown m. Hypertension. 2007 Jan;49(1):113-9. doi: 10.1161/01.HYP.0000249904.93940.7a. Epub 2006 Oct 30. Hypertension. 2007. PMID: 17075029
Genetic association analysis of inositol polyphosphate phosphatase-like 1 (INPPL1, SHIP2) variants with essential hypertension.
Marçano AC, Burke B, Gungadoo J, Wallace C, Kaisaki PJ, Woon PY, Farrall M, Clayton D, Brown M, Dominiczak A, Connell JM, Webster J, Lathrop M, Caulfield M, Samani N, Gauguier D, Munroe PB. Marçano AC, et al. Among authors: brown m. J Med Genet. 2007 Sep;44(9):603-5. doi: 10.1136/jmg.2007.049718. Epub 2007 Jun 8. J Med Genet. 2007. PMID: 17557929 Free PMC article.
Genome-wide association study identifies genes for biomarkers of cardiovascular disease: serum urate and dyslipidemia.
Wallace C, Newhouse SJ, Braund P, Zhang F, Tobin M, Falchi M, Ahmadi K, Dobson RJ, Marçano AC, Hajat C, Burton P, Deloukas P, Brown M, Connell JM, Dominiczak A, Lathrop GM, Webster J, Farrall M, Spector T, Samani NJ, Caulfield MJ, Munroe PB. Wallace C, et al. Among authors: brown m. Am J Hum Genet. 2008 Jan;82(1):139-49. doi: 10.1016/j.ajhg.2007.11.001. Am J Hum Genet. 2008. PMID: 18179892 Free PMC article.
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