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Nystatin biosynthesis and transport: nysH and nysG genes encoding a putative ABC transporter system in Streptomyces noursei ATCC 11455 are required for efficient conversion of 10-deoxynystatin to nystatin.
Sletta H, Borgos SE, Bruheim P, Sekurova ON, Grasdalen H, Aune R, Ellingsen TE, Zotchev SB. Sletta H, et al. Among authors: bruheim p. Antimicrob Agents Chemother. 2005 Nov;49(11):4576-83. doi: 10.1128/AAC.49.11.4576-4583.2005. Antimicrob Agents Chemother. 2005. PMID: 16251298 Free PMC article.
Candicidin biosynthesis gene cluster is widely distributed among Streptomyces spp. isolated from the sediments and the neuston layer of the Trondheim fjord, Norway.
Jørgensen H, Fjaervik E, Hakvåg S, Bruheim P, Bredholt H, Klinkenberg G, Ellingsen TE, Zotchev SB. Jørgensen H, et al. Among authors: bruheim p. Appl Environ Microbiol. 2009 May;75(10):3296-303. doi: 10.1128/AEM.02730-08. Epub 2009 Mar 13. Appl Environ Microbiol. 2009. PMID: 19286787 Free PMC article.
Biosynthesis of macrolactam BE-14106 involves two distinct PKS systems and amino acid processing enzymes for generation of the aminoacyl starter unit.
Jørgensen H, Degnes KF, Sletta H, Fjaervik E, Dikiy A, Herfindal L, Bruheim P, Klinkenberg G, Bredholt H, Nygård G, Døskeland SO, Ellingsen TE, Zotchev SB. Jørgensen H, et al. Among authors: bruheim p. Chem Biol. 2009 Oct 30;16(10):1109-21. doi: 10.1016/j.chembiol.2009.09.014. Chem Biol. 2009. PMID: 19875084
99 results