Bull HG - Search Results

1

Mouse and human granzyme B have distinct tetrapeptide specificities and abilities to recruit the bid pathway.

Casciola-Rosen L, Garcia-Calvo M, Bull HG, Becker JW, Hines T, Thornberry NA, Rosen A. Casciola-Rosen L, et al. Among authors: bull hg. J Biol Chem. 2007 Feb 16;282(7):4545-4552. doi: 10.1074/jbc.M606564200. Epub 2006 Dec 19. J Biol Chem. 2007. PMID: 17179148 Free article.

2

Discovery of potent, selective human granzyme B inhibitors that inhibit CTL mediated apoptosis.

Willoughby CA, Bull HG, Garcia-Calvo M, Jiang J, Chapman KT, Thornberry NA. Willoughby CA, et al. Among authors: bull hg. Bioorg Med Chem Lett. 2002 Aug 19;12(16):2197-200. doi: 10.1016/s0960-894x(02)00363-3. Bioorg Med Chem Lett. 2002. PMID: 12127536

3

The three-dimensional structure of human granzyme B compared to caspase-3, key mediators of cell death with cleavage specificity for aspartic acid in P1.

Rotonda J, Garcia-Calvo M, Bull HG, Geissler WM, McKeever BM, Willoughby CA, Thornberry NA, Becker JW. Rotonda J, et al. Among authors: bull hg. Chem Biol. 2001 Apr;8(4):357-68. doi: 10.1016/s1074-5521(01)00018-7. Chem Biol. 2001. PMID: 11325591

4

Adenovirus L4-100K assembly protein is a granzyme B substrate that potently inhibits granzyme B-mediated cell death.

Andrade F, Bull HG, Thornberry NA, Ketner GW, Casciola-Rosen LA, Rosen A. Andrade F, et al. Among authors: bull hg. Immunity. 2001 Jun;14(6):751-61. doi: 10.1016/s1074-7613(01)00149-2. Immunity. 2001. PMID: 11420045 Free article.

5

Mechanism-based inactivation of alanine racemase by 3-halovinylglycines.

Thornberry NA, Bull HG, Taub D, Wilson KE, Giménez-Gallego G, Rosegay A, Soderman DD, Patchett AA. Thornberry NA, et al. Among authors: bull hg. J Biol Chem. 1991 Nov 15;266(32):21657-65. J Biol Chem. 1991. PMID: 1939194 Free article.

6

The target of ezetimibe is Niemann-Pick C1-Like 1 (NPC1L1).

Garcia-Calvo M, Lisnock J, Bull HG, Hawes BE, Burnett DA, Braun MP, Crona JH, Davis HR Jr, Dean DC, Detmers PA, Graziano MP, Hughes M, Macintyre DE, Ogawa A, O'neill KA, Iyer SP, Shevell DE, Smith MM, Tang YS, Makarewicz AM, Ujjainwalla F, Altmann SW, Chapman KT, Thornberry NA. Garcia-Calvo M, et al. Among authors: bull hg. Proc Natl Acad Sci U S A. 2005 Jun 7;102(23):8132-7. doi: 10.1073/pnas.0500269102. Epub 2005 May 31. Proc Natl Acad Sci U S A. 2005. PMID: 15928087 Free PMC article.

7

Antistasin, a leech-derived inhibitor of factor Xa. Kinetic analysis of enzyme inhibition and identification of the reactive site.

Dunwiddie C, Thornberry NA, Bull HG, Sardana M, Friedman PA, Jacobs JW, Simpson E. Dunwiddie C, et al. Among authors: bull hg. J Biol Chem. 1989 Oct 5;264(28):16694-9. J Biol Chem. 1989. PMID: 2777803 Free article.

8

Rustmicin, a potent antifungal agent, inhibits sphingolipid synthesis at inositol phosphoceramide synthase.

Mandala SM, Thornton RA, Milligan J, Rosenbach M, Garcia-Calvo M, Bull HG, Harris G, Abruzzo GK, Flattery AM, Gill CJ, Bartizal K, Dreikorn S, Kurtz MB. Mandala SM, et al. Among authors: bull hg. J Biol Chem. 1998 Jun 12;273(24):14942-9. doi: 10.1074/jbc.273.24.14942. J Biol Chem. 1998. PMID: 9614099 Free article.

9

Khafrefungin, a novel inhibitor of sphingolipid synthesis.

Mandala SM, Thornton RA, Rosenbach M, Milligan J, Garcia-Calvo M, Bull HG, Kurtz MB. Mandala SM, et al. Among authors: bull hg. J Biol Chem. 1997 Dec 19;272(51):32709-14. doi: 10.1074/jbc.272.51.32709. J Biol Chem. 1997. PMID: 9405490 Free article.

10

Purification of angiotensin-converting enzyme from rabbit lung and human plasma by affinity chromatography.

Bull HG, Thornberry NA, Cordes EH. Bull HG, et al. J Biol Chem. 1985 Mar 10;260(5):2963-72. J Biol Chem. 1985. PMID: 2982846 Free article.

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