Burnett D - Search Results

1

Cyclic hydroxyamidines as amide isosteres: discovery of oxadiazolines and oxadiazines as potent and highly efficacious γ-secretase modulators in vivo.

Sun ZY, Asberom T, Bara T, Bennett C, Burnett D, Chu I, Clader J, Cohen-Williams M, Cole D, Czarniecki M, Durkin J, Gallo G, Greenlee W, Josien H, Huang X, Hyde L, Jones N, Kazakevich I, Li H, Liu X, Lee J, Maccoss M, Mandal MB, McCracken T, Nomeir A, Mazzola R, Palani A, Parker EM, Pissarnitski DA, Qin J, Song L, Terracina G, Vicarel M, Voigt J, Xu R, Zhang L, Zhang Q, Zhao Z, Zhu X, Zhu Z. Sun ZY, et al. Among authors: burnett d. J Med Chem. 2012 Jan 12;55(1):489-502. doi: 10.1021/jm201407j. Epub 2011 Dec 8. J Med Chem. 2012. PMID: 22098494

2

2-Azetidinones as inhibitors of cholesterol absorption.

Burnett DA, Caplen MA, Davis HR Jr, Burrier RE, Clader JW. Burnett DA, et al. J Med Chem. 1994 Jun 10;37(12):1733-6. doi: 10.1021/jm00038a001. J Med Chem. 1994. PMID: 8021912 No abstract available.

3

2-Azetidinone cholesterol absorption inhibitors: structure-activity relationships on the heterocyclic nucleus.

Clader JW, Burnett DA, Caplen MA, Domalski MS, Dugar S, Vaccaro W, Sher R, Browne ME, Zhao H, Burrier RE, Salisbury B, Davis HR Jr. Clader JW, et al. Among authors: burnett da. J Med Chem. 1996 Sep 13;39(19):3684-93. doi: 10.1021/jm960405n. J Med Chem. 1996. PMID: 8809157

4

Discovery of 1-(4-fluorophenyl)-(3R)-[3-(4-fluorophenyl)-(3S)-hydroxypropyl]-(4S)-(4 -hydroxyphenyl)-2-azetidinone (SCH 58235): a designed, potent, orally active inhibitor of cholesterol absorption.

Rosenblum SB, Huynh T, Afonso A, Davis HR Jr, Yumibe N, Clader JW, Burnett DA. Rosenblum SB, et al. Among authors: burnett da. J Med Chem. 1998 Mar 12;41(6):973-80. doi: 10.1021/jm970701f. J Med Chem. 1998. PMID: 9526571

5

Structure-activity relationships of pyrroloquinazolines as thrombin receptor antagonists.

Ahn HS, Arik L, Boykow G, Burnett DA, Caplen MA, Czarniecki M, Domalski MS, Foster C, Manna M, Stamford AW, Wu Y. Ahn HS, et al. Among authors: burnett da. Bioorg Med Chem Lett. 1999 Jul 19;9(14):2073-8. doi: 10.1016/s0960-894x(99)00339-x. Bioorg Med Chem Lett. 1999. PMID: 10450984

6

An enzymatic synthesis of glucuronides of azetidinone-based cholesterol absorption inhibitors.

Reiss P, Burnett DA, Zaks A. Reiss P, et al. Among authors: burnett da. Bioorg Med Chem. 1999 Oct;7(10):2199-202. doi: 10.1016/s0968-0896(99)00151-0. Bioorg Med Chem. 1999. PMID: 10579526

7

Synthesis of iodinated biochemical tools related to the 2-azetidinone class of cholesterol absorption inhibitors.

Burnett DA, Caplen MA, Domalski MS, Browne ME, Davis HR Jr, Clader JW. Burnett DA, et al. Bioorg Med Chem Lett. 2002 Feb 11;12(3):311-4. doi: 10.1016/s0960-894x(01)00750-8. Bioorg Med Chem Lett. 2002. PMID: 11814785

8

Synthesis of fluorescent biochemical tools related to the 2-azetidinone class of cholesterol absorption inhibitors.

Burnett DA, Caplen MA, Browne ME, Zhau H, Altmann SW, Davis HR, Clader JW. Burnett DA, et al. Bioorg Med Chem Lett. 2002 Feb 11;12(3):315-8. doi: 10.1016/s0960-894x(01)00752-1. Bioorg Med Chem Lett. 2002. PMID: 11814786

9

Synthesis and structure-activity relationships of aminoalkylazetidines as ORL1 receptor ligands.

Wu WL, Caplen MA, Domalski MS, Zhang H, Fawzi A, Burnett DA. Wu WL, et al. Bioorg Med Chem Lett. 2002 Nov 4;12(21):3157-60. doi: 10.1016/s0960-894x(02)00652-2. Bioorg Med Chem Lett. 2002. PMID: 12372523

10

Beta-lactam cholesterol absorption inhibitors.

Burnett DA. Burnett DA. Curr Med Chem. 2004 Jul;11(14):1873-87. doi: 10.2174/0929867043364865. Curr Med Chem. 2004. PMID: 15279572 Review.

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