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A porcine model of neurofibromatosis type 1 that mimics the human disease.
White KA, Swier VJ, Cain JT, Kohlmeyer JL, Meyerholz DK, Tanas MR, Uthoff J, Hammond E, Li H, Rohret FA, Goeken A, Chan CH, Leidinger MR, Umesalma S, Wallace MR, Dodd RD, Panzer K, Tang AH, Darbro BW, Moutal A, Cai S, Li W, Bellampalli SS, Khanna R, Rogers CS, Sieren JC, Quelle DE, Weimer JM. White KA, et al. Among authors: cai s. JCI Insight. 2018 Jun 21;3(12):e120402. doi: 10.1172/jci.insight.120402. eCollection 2018 Jun 21. JCI Insight. 2018. PMID: 29925695 Free PMC article.
CRISPR/Cas9 editing of Nf1 gene identifies CRMP2 as a therapeutic target in neurofibromatosis type 1-related pain that is reversed by (S)-Lacosamide.
Moutal A, Yang X, Li W, Gilbraith KB, Luo S, Cai S, François-Moutal L, Chew LA, Yeon SK, Bellampalli SS, Qu C, Xie JY, Ibrahim MM, Khanna M, Park KD, Porreca F, Khanna R. Moutal A, et al. Among authors: cai s. Pain. 2017 Dec;158(12):2301-2319. doi: 10.1097/j.pain.0000000000001002. Pain. 2017. PMID: 28809766 Free PMC article.
CRMP2 is necessary for Neurofibromatosis type 1 related pain.
Moutal A, Cai S, Luo S, Voisin R, Khanna R. Moutal A, et al. Among authors: cai s. Channels (Austin). 2018 Jan 1;12(1):47-50. doi: 10.1080/19336950.2017.1370524. Channels (Austin). 2018. PMID: 28837387 Free PMC article.
CRMP2-Neurofibromin Interface Drives NF1-related Pain.
Moutal A, Sun L, Yang X, Li W, Cai S, Luo S, Khanna R. Moutal A, et al. Among authors: cai s. Neuroscience. 2018 Jun 15;381:79-90. doi: 10.1016/j.neuroscience.2018.04.002. Epub 2018 Apr 12. Neuroscience. 2018. PMID: 29655575 Free PMC article.
Dissecting the role of the CRMP2-neurofibromin complex on pain behaviors.
Moutal A, Wang Y, Yang X, Ji Y, Luo S, Dorame A, Bellampalli SS, Chew LA, Cai S, Dustrude ET, Keener JE, Marty MT, Vanderah TW, Khanna R. Moutal A, et al. Among authors: cai s. Pain. 2017 Nov;158(11):2203-2221. doi: 10.1097/j.pain.0000000000001026. Pain. 2017. PMID: 28767512 Free PMC article.
Targeting T-type/CaV3.2 channels for chronic pain.
Cai S, Gomez K, Moutal A, Khanna R. Cai S, et al. Transl Res. 2021 Aug;234:20-30. doi: 10.1016/j.trsl.2021.01.002. Epub 2021 Jan 7. Transl Res. 2021. PMID: 33422652 Free PMC article. Review.
6,517 results