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Mitochondrial health is enhanced in rats with higher vs. lower intrinsic exercise capacity and extended lifespan.
Aon MA, Cortassa S, Juhaszova M, González-Reyes JA, Calvo-Rubio M, Villalba JM, Lachance AD, Ziman BD, Mitchell SJ, Murt KN, Axsom JEC, Alfaras I, Britton SL, Koch LG, de Cabo R, Lakatta EG, Sollott SJ. Aon MA, et al. Among authors: calvo rubio m. NPJ Aging Mech Dis. 2021 Jan 4;7(1):1. doi: 10.1038/s41514-020-00054-3. NPJ Aging Mech Dis. 2021. PMID: 33398019 Free PMC article.
The influence of dietary fat source on liver and skeletal muscle mitochondrial modifications and lifespan changes in calorie-restricted mice.
Villalba JM, López-Domínguez JA, Chen Y, Khraiwesh H, González-Reyes JA, Del Río LF, Gutiérrez-Casado E, Del Río M, Calvo-Rubio M, Ariza J, de Cabo R, López-Lluch G, Navas P, Hagopian K, Burón MI, Ramsey JJ. Villalba JM, et al. Among authors: calvo rubio m. Biogerontology. 2015 Oct;16(5):655-70. doi: 10.1007/s10522-015-9572-1. Epub 2015 Apr 10. Biogerontology. 2015. PMID: 25860863 Free PMC article. Review.
Effects of Sex, Strain, and Energy Intake on Hallmarks of Aging in Mice.
Mitchell SJ, Madrigal-Matute J, Scheibye-Knudsen M, Fang E, Aon M, González-Reyes JA, Cortassa S, Kaushik S, Gonzalez-Freire M, Patel B, Wahl D, Ali A, Calvo-Rubio M, Burón MI, Guiterrez V, Ward TM, Palacios HH, Cai H, Frederick DW, Hine C, Broeskamp F, Habering L, Dawson J, Beasley TM, Wan J, Ikeno Y, Hubbard G, Becker KG, Zhang Y, Bohr VA, Longo DL, Navas P, Ferrucci L, Sinclair DA, Cohen P, Egan JM, Mitchell JR, Baur JA, Allison DB, Anson RM, Villalba JM, Madeo F, Cuervo AM, Pearson KJ, Ingram DK, Bernier M, de Cabo R. Mitchell SJ, et al. Among authors: calvo rubio m. Cell Metab. 2016 Jun 14;23(6):1093-1112. doi: 10.1016/j.cmet.2016.05.027. Cell Metab. 2016. PMID: 27304509 Free PMC article.
Overexpression of CYB5R3 and NQO1, two NAD+ -producing enzymes, mimics aspects of caloric restriction.
Diaz-Ruiz A, Lanasa M, Garcia J, Mora H, Fan F, Martin-Montalvo A, Di Francesco A, Calvo-Rubio M, Salvador-Pascual A, Aon MA, Fishbein KW, Pearson KJ, Villalba JM, Navas P, Bernier M, de Cabo R. Diaz-Ruiz A, et al. Among authors: calvo rubio m. Aging Cell. 2018 Aug;17(4):e12767. doi: 10.1111/acel.12767. Epub 2018 Apr 28. Aging Cell. 2018. PMID: 29706024 Free PMC article.
Age-dependent impact of two exercise training regimens on genomic and metabolic remodeling in skeletal muscle and liver of male mice.
Bernier M, Enamorado IN, Gómez-Cabrera MC, Calvo-Rubio M, González-Reyes JA, Price NL, Cortés-Rodríguez AB, Rodríguez-Aguilera JC, Rodríguez-López S, Mitchell SJ, Murt KN, Kalafut K, Williams KM, Ward CW, Stains JP, Brea-Calvo G, Villalba JM, Cortassa S, Aon MA, de Cabo R. Bernier M, et al. Among authors: calvo rubio m. NPJ Aging. 2022 Jun 27;8(1):8. doi: 10.1038/s41514-022-00089-8. NPJ Aging. 2022. PMID: 35927269 Free PMC article.
Sex-specific metabolic adaptations in transgenic mice overexpressing cytochrome b5 reductase-3.
Sánchez-Mendoza LM, Pérez-Sánchez C, Rodríguez-López S, López-Pedrera C, Calvo-Rubio M, de Cabo R, Burón MI, González-Reyes JA, Villalba JM. Sánchez-Mendoza LM, et al. Among authors: calvo rubio m. Free Radic Biol Med. 2023 Oct;207:144-160. doi: 10.1016/j.freeradbiomed.2023.07.012. Epub 2023 Jul 16. Free Radic Biol Med. 2023. PMID: 37463636 Free article.
The YAP-TEAD complex promotes senescent cell survival by lowering endoplasmic reticulum stress.
Anerillas C, Mazan-Mamczarz K, Herman AB, Munk R, Lam KG, Calvo-Rubio M, Garrido A, Tsitsipatis D, Martindale JL, Altés G, Rossi M, Piao Y, Fan J, Cui CY, De S, Abdelmohsen K, de Cabo R, Gorospe M. Anerillas C, et al. Among authors: calvo rubio m. Nat Aging. 2023 Oct;3(10):1237-1250. doi: 10.1038/s43587-023-00480-4. Epub 2023 Sep 4. Nat Aging. 2023. PMID: 37667102
Soluble epoxide hydrolase in podocytes is a significant contributor to renal function under hyperglycemia.
Bettaieb A, Koike S, Hsu MF, Ito Y, Chahed S, Bachaalany S, Gruzdev A, Calvo-Rubio M, Lee KSS, Inceoglu B, Imig JD, Villalba JM, Zeldin DC, Hammock BD, Haj FG. Bettaieb A, et al. Among authors: calvo rubio m. Biochim Biophys Acta Gen Subj. 2017 Nov;1861(11 Pt A):2758-2765. doi: 10.1016/j.bbagen.2017.07.021. Epub 2017 Jul 27. Biochim Biophys Acta Gen Subj. 2017. PMID: 28757338 Free PMC article.
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