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Targeting tumour hypoxia to prevent cancer metastasis. From biology, biosensing and technology to drug development: the METOXIA consortium.
Pettersen EO, Ebbesen P, Gieling RG, Williams KJ, Dubois L, Lambin P, Ward C, Meehan J, Kunkler IH, Langdon SP, Ree AH, Flatmark K, Lyng H, Calzada MJ, Peso LD, Landazuri MO, Görlach A, Flamm H, Kieninger J, Urban G, Weltin A, Singleton DC, Haider S, Buffa FM, Harris AL, Scozzafava A, Supuran CT, Moser I, Jobst G, Busk M, Toustrup K, Overgaard J, Alsner J, Pouyssegur J, Chiche J, Mazure N, Marchiq I, Parks S, Ahmed A, Ashcroft M, Pastorekova S, Cao Y, Rouschop KM, Wouters BG, Koritzinsky M, Mujcic H, Cojocari D. Pettersen EO, et al. Among authors: calzada mj. J Enzyme Inhib Med Chem. 2015;30(5):689-721. doi: 10.3109/14756366.2014.966704. Epub 2014 Oct 27. J Enzyme Inhib Med Chem. 2015. PMID: 25347767 Review.
Inadequate activation of the GTPase RhoA contributes to the lack of fibronectin matrix assembly in von Hippel-Lindau protein-defective renal cancer cells.
Feijóo-Cuaresma M, Méndez F, Maqueda A, Esteban MA, Naranjo-Suarez S, Castellanos MC, del Cerro MH, Vazquez SN, García-Pardo A, Landázuri MO, Calzada MJ. Feijóo-Cuaresma M, et al. Among authors: calzada mj. J Biol Chem. 2008 Sep 5;283(36):24982-90. doi: 10.1074/jbc.M709390200. Epub 2008 Jun 19. J Biol Chem. 2008. PMID: 18567581 Free PMC article.
Hypoxia-inducible factors and cancer.
Calzada MJ, del Peso L. Calzada MJ, et al. Clin Transl Oncol. 2007 May;9(5):278-89. doi: 10.1007/s12094-007-0055-y. Clin Transl Oncol. 2007. PMID: 17525038 Review.
Thrombospondin-1/CD47 Interaction Regulates Th17 and Treg Differentiation in Psoriasis.
Rodríguez-Jiménez P, Chicharro P, Llamas-Velasco M, Cibrian D, Trigo-Torres L, Vara A, Jiménez-Fernández M, Sevilla-Montero J, Calzada MJ, Sánchez-Madrid F, de la Fuente H, Daudén E. Rodríguez-Jiménez P, et al. Among authors: calzada mj. Front Immunol. 2019 Jun 4;10:1268. doi: 10.3389/fimmu.2019.01268. eCollection 2019. Front Immunol. 2019. PMID: 31214201 Free PMC article.
COVID-19 severity associates with pulmonary redistribution of CD1c+ DCs and inflammatory transitional and nonclassical monocytes.
Sánchez-Cerrillo I, Landete P, Aldave B, Sánchez-Alonso S, Sánchez-Azofra A, Marcos-Jiménez A, Ávalos E, Alcaraz-Serna A, de Los Santos I, Mateu-Albero T, Esparcia L, López-Sanz C, Martínez-Fleta P, Gabrie L, Del Campo Guerola L, de la Fuente H, Calzada MJ, González-Álvaro I, Alfranca A, Sánchez-Madrid F, Muñoz-Calleja C, Soriano JB, Ancochea J, Martín-Gayo E; REINMUN-COVID and EDEPIMIC groups. Sánchez-Cerrillo I, et al. Among authors: calzada mj. J Clin Invest. 2020 Dec 1;130(12):6290-6300. doi: 10.1172/JCI140335. J Clin Invest. 2020. PMID: 32784290 Free PMC article. Clinical Trial.
39 results