Cameron J - Search Results

1

Interaction with both domain I and III of albumin is required for optimal pH-dependent binding to the neonatal Fc receptor (FcRn).

Sand KM, Bern M, Nilsen J, Dalhus B, Gunnarsen KS, Cameron J, Grevys A, Bunting K, Sandlie I, Andersen JT. Sand KM, et al. Among authors: cameron j. J Biol Chem. 2014 Dec 12;289(50):34583-94. doi: 10.1074/jbc.M114.587675. Epub 2014 Oct 24. J Biol Chem. 2014. PMID: 25344603 Free PMC article.

2

Structure-based mutagenesis reveals the albumin-binding site of the neonatal Fc receptor.

Andersen JT, Dalhus B, Cameron J, Daba MB, Plumridge A, Evans L, Brennan SO, Gunnarsen KS, Bjørås M, Sleep D, Sandlie I. Andersen JT, et al. Among authors: cameron j. Nat Commun. 2012 Jan 3;3:610. doi: 10.1038/ncomms1607. Nat Commun. 2012. PMID: 22215085 Free PMC article.

3

Albumin as a versatile platform for drug half-life extension.

Sleep D, Cameron J, Evans LR. Sleep D, et al. Among authors: cameron j. Biochim Biophys Acta. 2013 Dec;1830(12):5526-34. doi: 10.1016/j.bbagen.2013.04.023. Epub 2013 Apr 29. Biochim Biophys Acta. 2013. PMID: 23639804 Review.

4

Single-chain variable fragment albumin fusions bind the neonatal Fc receptor (FcRn) in a species-dependent manner: implications for in vivo half-life evaluation of albumin fusion therapeutics.

Andersen JT, Cameron J, Plumridge A, Evans L, Sleep D, Sandlie I. Andersen JT, et al. Among authors: cameron j. J Biol Chem. 2013 Aug 16;288(33):24277-85. doi: 10.1074/jbc.M113.463000. Epub 2013 Jul 1. J Biol Chem. 2013. PMID: 23818524 Free PMC article.

5

Extending serum half-life of albumin by engineering neonatal Fc receptor (FcRn) binding.

Andersen JT, Dalhus B, Viuff D, Ravn BT, Gunnarsen KS, Plumridge A, Bunting K, Antunes F, Williamson R, Athwal S, Allan E, Evans L, Bjørås M, Kjærulff S, Sleep D, Sandlie I, Cameron J. Andersen JT, et al. Among authors: cameron j. J Biol Chem. 2014 May 9;289(19):13492-502. doi: 10.1074/jbc.M114.549832. Epub 2014 Mar 20. J Biol Chem. 2014. PMID: 24652290 Free PMC article.

6

Dissection of the neonatal Fc receptor (FcRn)-albumin interface using mutagenesis and anti-FcRn albumin-blocking antibodies.

Sand KM, Dalhus B, Christianson GJ, Bern M, Foss S, Cameron J, Sleep D, Bjørås M, Roopenian DC, Sandlie I, Andersen JT. Sand KM, et al. Among authors: cameron j. J Biol Chem. 2014 Jun 13;289(24):17228-39. doi: 10.1074/jbc.M113.522565. Epub 2014 Apr 24. J Biol Chem. 2014. PMID: 24764301 Free PMC article.

7

Neonatal Fc Receptor Binding Tolerance toward the Covalent Conjugation of Payloads to Cysteine 34 of Human Albumin Variants.

Petersen SS, Kläning E, Ebbesen MF, Andersen B, Cameron J, Sørensen ES, Howard KA. Petersen SS, et al. Among authors: cameron j. Mol Pharm. 2016 Feb 1;13(2):677-82. doi: 10.1021/acs.molpharmaceut.5b00605. Epub 2015 Dec 29. Mol Pharm. 2016. PMID: 26654692

8

Generation of a double transgenic humanized neonatal Fc receptor (FcRn)/albumin mouse to study the pharmacokinetics of albumin-linked drugs.

Viuff D, Antunes F, Evans L, Cameron J, Dyrnesli H, Thue Ravn B, Stougaard M, Thiam K, Andersen B, Kjærulff S, Howard KA. Viuff D, et al. Among authors: cameron j. J Control Release. 2016 Feb 10;223:22-30. doi: 10.1016/j.jconrel.2015.12.019. Epub 2015 Dec 14. J Control Release. 2016. PMID: 26699424

9

Albumin-based drug delivery using cysteine 34 chemical conjugates - important considerations and requirements.

Caspersen MB, Kuhlmann M, Nicholls K, Saxton MJ, Andersen B, Bunting K, Cameron J, Howard KA. Caspersen MB, et al. Among authors: cameron j. Ther Deliv. 2017 Jul;8(7):511-519. doi: 10.4155/tde-2017-0038. Epub 2017 May 30. Ther Deliv. 2017. PMID: 28555530

10

Direct demonstration of a neonatal Fc receptor (FcRn)-driven endosomal sorting pathway for cellular recycling of albumin.

Schmidt EGW, Hvam ML, Antunes F, Cameron J, Viuff D, Andersen B, Kristensen NN, Howard KA. Schmidt EGW, et al. Among authors: cameron j. J Biol Chem. 2017 Aug 11;292(32):13312-13322. doi: 10.1074/jbc.M117.794248. Epub 2017 Jun 21. J Biol Chem. 2017. PMID: 28637874 Free PMC article.

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