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Page 1
A GWAS in Latin Americans identifies novel face shape loci, implicating VPS13B and a Denisovan introgressed region in facial variation.
Bonfante B, Faux P, Navarro N, Mendoza-Revilla J, Dubied M, Montillot C, Wentworth E, Poloni L, Varón-González C, Jones P, Xiong Z, Fuentes-Guajardo M, Palmal S, Chacón-Duque JC, Hurtado M, Villegas V, Granja V, Jaramillo C, Arias W, Barquera R, Everardo-Martínez P, Sánchez-Quinto M, Gómez-Valdés J, Villamil-Ramírez H, Silva de Cerqueira CC, Hünemeier T, Ramallo V, Liu F, Weinberg SM, Shaffer JR, Stergiakouli E, Howe LJ, Hysi PG, Spector TD, Gonzalez-José R, Schüler-Faccini L, Bortolini MC, Acuña-Alonzo V, Canizales-Quinteros S, Gallo C, Poletti G, Bedoya G, Rothhammer F, Thauvin-Robinet C, Faivre L, Costedoat C, Balding D, Cox T, Kayser M, Duplomb L, Yalcin B, Cotney J, Adhikari K, Ruiz-Linares A. Bonfante B, et al. Sci Adv. 2021 Feb 5;7(6):eabc6160. doi: 10.1126/sciadv.abc6160. Print 2021 Feb. Sci Adv. 2021. PMID: 33547071 Free PMC article.
A functional ABCA1 gene variant is associated with low HDL-cholesterol levels and shows evidence of positive selection in Native Americans.
Acuña-Alonzo V, Flores-Dorantes T, Kruit JK, Villarreal-Molina T, Arellano-Campos O, Hünemeier T, Moreno-Estrada A, Ortiz-López MG, Villamil-Ramírez H, León-Mimila P, Villalobos-Comparan M, Jacobo-Albavera L, Ramírez-Jiménez S, Sikora M, Zhang LH, Pape TD, Granados-Silvestre Mde A, Montufar-Robles I, Tito-Alvarez AM, Zurita-Salinas C, Bustos-Arriaga J, Cedillo-Barrón L, Gómez-Trejo C, Barquera-Lozano R, Vieira-Filho JP, Granados J, Romero-Hidalgo S, Huertas-Vázquez A, González-Martín A, Gorostiza A, Bonatto SL, Rodríguez-Cruz M, Wang L, Tusié-Luna T, Aguilar-Salinas CA, Lisker R, Moises RS, Menjivar M, Salzano FM, Knowler WC, Bortolini MC, Hayden MR, Baier LJ, Canizales-Quinteros S. Acuña-Alonzo V, et al. Hum Mol Genet. 2010 Jul 15;19(14):2877-85. doi: 10.1093/hmg/ddq173. Epub 2010 Apr 23. Hum Mol Genet. 2010. PMID: 20418488 Free PMC article.
PCSK1 rs6232 is associated with childhood and adult class III obesity in the Mexican population.
Villalobos-Comparán M, Villamil-Ramírez H, Villarreal-Molina T, Larrieta-Carrasco E, León-Mimila P, Romero-Hidalgo S, Jacobo-Albavera L, Liceaga-Fuentes AE, Campos-Pérez FJ, López-Contreras BE, Tusié-Luna T, Del Río-Navarro BE, Aguilar-Salinas CA, Canizales-Quinteros S. Villalobos-Comparán M, et al. PLoS One. 2012;7(6):e39037. doi: 10.1371/journal.pone.0039037. Epub 2012 Jun 21. PLoS One. 2012. PMID: 22737226 Free PMC article.
Evolutionary responses to a constructed niche: ancient Mesoamericans as a model of gene-culture coevolution.
Hünemeier T, Amorim CE, Azevedo S, Contini V, Acuña-Alonzo V, Rothhammer F, Dugoujon JM, Mazières S, Barrantes R, Villarreal-Molina MT, Paixão-Côrtes VR, Salzano FM, Canizales-Quinteros S, Ruiz-Linares A, Bortolini MC. Hünemeier T, et al. PLoS One. 2012;7(6):e38862. doi: 10.1371/journal.pone.0038862. Epub 2012 Jun 21. PLoS One. 2012. PMID: 22768049 Free PMC article.
Reconstructing Native American population history.
Reich D, Patterson N, Campbell D, Tandon A, Mazieres S, Ray N, Parra MV, Rojas W, Duque C, Mesa N, García LF, Triana O, Blair S, Maestre A, Dib JC, Bravi CM, Bailliet G, Corach D, Hünemeier T, Bortolini MC, Salzano FM, Petzl-Erler ML, Acuña-Alonzo V, Aguilar-Salinas C, Canizales-Quinteros S, Tusié-Luna T, Riba L, Rodríguez-Cruz M, Lopez-Alarcón M, Coral-Vazquez R, Canto-Cetina T, Silva-Zolezzi I, Fernandez-Lopez JC, Contreras AV, Jimenez-Sanchez G, Gómez-Vázquez MJ, Molina J, Carracedo A, Salas A, Gallo C, Poletti G, Witonsky DB, Alkorta-Aranburu G, Sukernik RI, Osipova L, Fedorova SA, Vasquez R, Villena M, Moreau C, Barrantes R, Pauls D, Excoffier L, Bedoya G, Rothhammer F, Dugoujon JM, Larrouy G, Klitz W, Labuda D, Kidd J, Kidd K, Di Rienzo A, Freimer NB, Price AL, Ruiz-Linares A. Reich D, et al. Nature. 2012 Aug 16;488(7411):370-4. doi: 10.1038/nature11258. Nature. 2012. PMID: 22801491 Free PMC article.
Fibroblast growth factor receptor 1 (FGFR1) variants and craniofacial variation in Amerindians and related populations.
Gómez-Valdés JA, Hünemeier T, Contini V, Acuña-Alonzo V, Macin G, Ballesteros-Romero M, Corral P, Ruiz-Linares A, Sánchez-Mejorada G, Canizales-Quinteros S, Martínez-Abadías N, Salzano FM, González-José R, Bortolini MC. Gómez-Valdés JA, et al. Am J Hum Biol. 2013 Jan-Feb;25(1):12-9. doi: 10.1002/ajhb.22331. Epub 2012 Oct 16. Am J Hum Biol. 2013. PMID: 23070782
Contribution of common genetic variants to obesity and obesity-related traits in mexican children and adults.
León-Mimila P, Villamil-Ramírez H, Villalobos-Comparán M, Villarreal-Molina T, Romero-Hidalgo S, López-Contreras B, Gutiérrez-Vidal R, Vega-Badillo J, Jacobo-Albavera L, Posadas-Romeros C, Canizalez-Román A, Río-Navarro BD, Campos-Pérez F, Acuña-Alonzo V, Aguilar-Salinas C, Canizales-Quinteros S. León-Mimila P, et al. PLoS One. 2013 Aug 8;8(8):e70640. doi: 10.1371/journal.pone.0070640. eCollection 2013. PLoS One. 2013. PMID: 23950976 Free PMC article.
Implications of the admixture process in skin color molecular assessment.
Cerqueira CC, Hünemeier T, Gomez-Valdés J, Ramallo V, Volasko-Krause CD, Barbosa AA, Vargas-Pinilla P, Dornelles RC, Longo D, Rothhammer F, Bedoya G, Canizales-Quinteros S, Acuña-Alonzo V, Gallo C, Poletti G, González-José R, Salzano FM, Callegari-Jacques SM, Schuler-Faccini L, Ruiz-Linares A, Cátira Bortolini M; for CANDELA (Consortium for the Analysis of the Diversity and Evolution of Latin America). Cerqueira CC, et al. PLoS One. 2014 May 8;9(5):e96886. doi: 10.1371/journal.pone.0096886. eCollection 2014. PLoS One. 2014. PMID: 24809478 Free PMC article.
Human genetics. The genetics of Mexico recapitulates Native American substructure and affects biomedical traits.
Moreno-Estrada A, Gignoux CR, Fernández-López JC, Zakharia F, Sikora M, Contreras AV, Acuña-Alonzo V, Sandoval K, Eng C, Romero-Hidalgo S, Ortiz-Tello P, Robles V, Kenny EE, Nuño-Arana I, Barquera-Lozano R, Macín-Pérez G, Granados-Arriola J, Huntsman S, Galanter JM, Via M, Ford JG, Chapela R, Rodriguez-Cintron W, Rodríguez-Santana JR, Romieu I, Sienra-Monge JJ, del Rio Navarro B, London SJ, Ruiz-Linares A, Garcia-Herrera R, Estrada K, Hidalgo-Miranda A, Jimenez-Sanchez G, Carnevale A, Soberón X, Canizales-Quinteros S, Rangel-Villalobos H, Silva-Zolezzi I, Burchard EG, Bustamante CD. Moreno-Estrada A, et al. Science. 2014 Jun 13;344(6189):1280-5. doi: 10.1126/science.1251688. Epub 2014 Jun 12. Science. 2014. PMID: 24926019 Free PMC article.
143 results