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Reptin/Ruvbl2 is a Lrrc6/Seahorse interactor essential for cilia motility.
Zhao L, Yuan S, Cao Y, Kallakuri S, Li Y, Kishimoto N, DiBella L, Sun Z. Zhao L, et al. Among authors: cao y. Proc Natl Acad Sci U S A. 2013 Jul 30;110(31):12697-702. doi: 10.1073/pnas.1300968110. Epub 2013 Jul 15. Proc Natl Acad Sci U S A. 2013. PMID: 23858445 Free PMC article.
Impaired Hippo signaling promotes Rho1-JNK-dependent growth.
Ma X, Chen Y, Xu W, Wu N, Li M, Cao Y, Wu S, Li Q, Xue L. Ma X, et al. Among authors: cao y. Proc Natl Acad Sci U S A. 2015 Jan 27;112(4):1065-70. doi: 10.1073/pnas.1415020112. Epub 2015 Jan 12. Proc Natl Acad Sci U S A. 2015. PMID: 25583514 Free PMC article.
Apical PtdIns(4,5)P2 is required for ciliogenesis and suppression of polycystic kidney disease.
Xu W, Jin M, Huang W, Wang H, Hu R, Li J, Cao Y. Xu W, et al. Among authors: cao y. FASEB J. 2019 Feb;33(2):2848-2857. doi: 10.1096/fj.201800385RRR. Epub 2018 Oct 15. FASEB J. 2019. PMID: 30321068
Taken together, our results reveal that apical PtdIns(4,5)P(2) is essential for ciliogenesis and the prevention of PKD and suggest a novel possibility for treating PKD and other human ciliopathies.-Xu, W., Jin, M., Huang, W., Wang, H., Hu, R., Li, J., Cao, Y. Apical …
Taken together, our results reveal that apical PtdIns(4,5)P(2) is essential for ciliogenesis and the prevention of PKD and suggest a novel p …
WDR31 displays functional redundancy with GTPase-activating proteins (GAPs) ELMOD and RP2 in regulating IFT complex and recruiting the BBSome to cilium.
Cevik S, Peng X, Beyer T, Pir MS, Yenisert F, Woerz F, Hoffmann F, Altunkaynak B, Pir B, Boldt K, Karaman A, Cakiroglu M, Oner SS, Cao Y, Ueffing M, Kaplan OI. Cevik S, et al. Among authors: cao y. Life Sci Alliance. 2023 May 19;6(8):e202201844. doi: 10.26508/lsa.202201844. Print 2023 Aug. Life Sci Alliance. 2023. PMID: 37208194 Free PMC article.
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