Apical PtdIns(4,5)P2 is required for ciliogenesis and suppression of polycystic kidney disease.
Xu W, Jin M, Huang W, Wang H, Hu R, Li J, Cao Y.
Xu W, et al. Among authors: cao y.
FASEB J. 2019 Feb;33(2):2848-2857. doi: 10.1096/fj.201800385RRR. Epub 2018 Oct 15.
FASEB J. 2019.
PMID: 30321068
Taken together, our results reveal that apical PtdIns(4,5)P(2) is essential for ciliogenesis and the prevention of PKD and suggest a novel possibility for treating PKD and other human ciliopathies.-Xu, W., Jin, M., Huang, W., Wang, H., Hu, R., Li, J., Cao, Y. Apical …
Taken together, our results reveal that apical PtdIns(4,5)P(2) is essential for ciliogenesis and the prevention of PKD and suggest a novel p …