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114 results

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Anastrozole Aromatase Inhibitor Plasma Drug Concentration Genome-Wide Association Study: Functional Epistatic Interaction Between SLC38A7 and ALPPL2.
Dudenkov TM, Liu D, Cairns J, Devarajan S, Zhuang Y, Ingle JN, Buzdar AU, Robson ME, Kubo M, Batzler A, Barman P, Jenkins GD, Carlson EE, Goetz MP, Northfelt DW, Moreno-Aspitia A, Desta Z, Reid JM, Kalari KR, Wang L, Weinshilboum RM. Dudenkov TM, et al. Among authors: carlson ee. Clin Pharmacol Ther. 2019 Jul;106(1):219-227. doi: 10.1002/cpt.1359. Epub 2019 Mar 18. Clin Pharmacol Ther. 2019. PMID: 30648747 Free PMC article.
TSPYL5 SNPs: association with plasma estradiol concentrations and aromatase expression.
Liu M, Ingle JN, Fridley BL, Buzdar AU, Robson ME, Kubo M, Wang L, Batzler A, Jenkins GD, Pietrzak TL, Carlson EE, Goetz MP, Northfelt DW, Perez EA, Williard CV, Schaid DJ, Nakamura Y, Weinshilboum RM. Liu M, et al. Among authors: carlson ee. Mol Endocrinol. 2013 Apr;27(4):657-70. doi: 10.1210/me.2012-1397. Epub 2013 Mar 21. Mol Endocrinol. 2013. PMID: 23518928 Free PMC article. Clinical Trial.
Aromatase inhibitor-associated bone fractures: a case-cohort GWAS and functional genomics.
Liu M, Goss PE, Ingle JN, Kubo M, Furukawa Y, Batzler A, Jenkins GD, Carlson EE, Nakamura Y, Schaid DJ, Chapman JA, Shepherd LE, Ellis MJ, Khosla S, Wang L, Weinshilboum RM. Liu M, et al. Among authors: carlson ee. Mol Endocrinol. 2014 Oct;28(10):1740-51. doi: 10.1210/me.2014-1147. Epub 2014 Aug 22. Mol Endocrinol. 2014. PMID: 25148458 Free PMC article. Clinical Trial.
Genetic Polymorphisms in the Long Noncoding RNA MIR2052HG Offer a Pharmacogenomic Basis for the Response of Breast Cancer Patients to Aromatase Inhibitor Therapy.
Ingle JN, Xie F, Ellis MJ, Goss PE, Shepherd LE, Chapman JW, Chen BE, Kubo M, Furukawa Y, Momozawa Y, Stearns V, Pritchard KI, Barman P, Carlson EE, Goetz MP, Weinshilboum RM, Kalari KR, Wang L. Ingle JN, et al. Among authors: carlson ee. Cancer Res. 2016 Dec 1;76(23):7012-7023. doi: 10.1158/0008-5472.CAN-16-1371. Epub 2016 Oct 10. Cancer Res. 2016. PMID: 27758888 Free PMC article.
SLCO1B1 polymorphisms and plasma estrone conjugates in postmenopausal women with ER+ breast cancer: genome-wide association studies of the estrone pathway.
Dudenkov TM, Ingle JN, Buzdar AU, Robson ME, Kubo M, Ibrahim-Zada I, Batzler A, Jenkins GD, Pietrzak TL, Carlson EE, Barman P, Goetz MP, Northfelt DW, Moreno-Aspita A, Williard CV, Kalari KR, Nakamura Y, Wang L, Weinshilboum RM. Dudenkov TM, et al. Among authors: carlson ee. Breast Cancer Res Treat. 2017 Jul;164(1):189-199. doi: 10.1007/s10549-017-4243-3. Epub 2017 Apr 20. Breast Cancer Res Treat. 2017. PMID: 28429243 Free PMC article.
Germline genome-wide association studies in women receiving neoadjuvant chemotherapy with or without bevacizumab.
Ingle JN, Kalari KR, Wickerham DL, von Minckwitz G, Fasching PA, Furukawa Y, Mushiroda T, Goetz MP, Barman P, Carlson EE, Rastogi P, Costantino JP, Cairns J, Paik S, Bear HD, Kubo M, Wang L, Wolmark N, Weinshilboum RM. Ingle JN, et al. Among authors: carlson ee. Pharmacogenet Genomics. 2018 Jun;28(6):147-152. doi: 10.1097/FPC.0000000000000337. Pharmacogenet Genomics. 2018. PMID: 29768301 Free PMC article. Clinical Trial.
Deep sequencing across germline genome-wide association study signals relating to breast cancer events in women receiving aromatase inhibitors for adjuvant therapy of early breast cancer.
Ingle JN, Kalari KR, Momozawa Y, Kubo M, Furukawa Y, Shepherd LE, Ellis MJ, Goss PE, Barman P, Carlson EE, Sinnwell JP, Tang X, Goetz MP, Chen BE, Cairns J, Weinshilboum RM, Wang L. Ingle JN, et al. Among authors: carlson ee. Pharmacogenet Genomics. 2019 Oct;29(8):183-191. doi: 10.1097/FPC.0000000000000382. Pharmacogenet Genomics. 2019. PMID: 31211741 Free PMC article.
Anastrozole has an Association between Degree of Estrogen Suppression and Outcomes in Early Breast Cancer and is a Ligand for Estrogen Receptor α.
Ingle JN, Cairns J, Suman VJ, Shepherd LE, Fasching PA, Hoskin TL, Singh RJ, Desta Z, Kalari KR, Ellis MJ, Goss PE, Chen BE, Volz B, Barman P, Carlson EE, Haddad T, Goetz MP, Goodnature B, Cuellar ME, Walters MA, Correia C, Kaufmann SH, Weinshilboum RM, Wang L. Ingle JN, et al. Among authors: carlson ee. Clin Cancer Res. 2020 Jun 15;26(12):2986-2996. doi: 10.1158/1078-0432.CCR-19-3091. Epub 2020 Feb 25. Clin Cancer Res. 2020. PMID: 32098767 Free PMC article.
Single-nucleotide polymorphism biomarkers of adjuvant anastrozole-induced estrogen suppression in early breast cancer.
Ingle JN, Kalari KR, Barman P, Shepherd LE, Ellis MJ, Goss PE, Buzdar AU, Robson ME, Cairns J, Carlson EE, Eyman Casey A, Hoskin TL, Goodnature BA, Haddad TC, Goetz MP, Weinshilboum RM, Wang L. Ingle JN, et al. Among authors: carlson ee. Pharmacogenet Genomics. 2021 Jan;31(1):1-9. doi: 10.1097/FPC.0000000000000415. Pharmacogenet Genomics. 2021. PMID: 32649577 Free PMC article.
Pharmacogenomics of aromatase inhibitors in postmenopausal breast cancer and additional mechanisms of anastrozole action.
Cairns J, Ingle JN, Dudenkov TM, Kalari KR, Carlson EE, Na J, Buzdar AU, Robson ME, Ellis MJ, Goss PE, Shepherd LE, Goodnature B, Goetz MP, Weinshilboum RM, Li H, Bari MG, Wang L. Cairns J, et al. Among authors: carlson ee. JCI Insight. 2020 Aug 20;5(16):e137571. doi: 10.1172/jci.insight.137571. JCI Insight. 2020. PMID: 32701512 Free PMC article. Clinical Trial.
114 results