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MT5-MMP is a new pro-amyloidogenic proteinase that promotes amyloid pathology and cognitive decline in a transgenic mouse model of Alzheimer's disease.
Baranger K, Marchalant Y, Bonnet AE, Crouzin N, Carrete A, Paumier JM, Py NA, Bernard A, Bauer C, Charrat E, Moschke K, Seiki M, Vignes M, Lichtenthaler SF, Checler F, Khrestchatisky M, Rivera S. Baranger K, et al. Among authors: carrete a. Cell Mol Life Sci. 2016 Jan;73(1):217-36. doi: 10.1007/s00018-015-1992-1. Epub 2015 Jul 23. Cell Mol Life Sci. 2016. PMID: 26202697 Free PMC article.
Targeting demyelination via α-secretases promoting sAPPα release to enhance remyelination in central nervous system.
Llufriu-Dabén G, Carrete A, Chierto E, Mailleux J, Camand E, Simon A, Vanmierlo T, Rose C, Allinquant B, Hendriks JJA, Massaad C, Meffre D, Jafarian-Tehrani M. Llufriu-Dabén G, et al. Among authors: carrete a. Neurobiol Dis. 2018 Jan;109(Pt A):11-24. doi: 10.1016/j.nbd.2017.09.008. Epub 2017 Sep 18. Neurobiol Dis. 2018. PMID: 28923597
Mechanical Stretch of High Magnitude Provokes Axonal Injury, Elongation of Paranodal Junctions, and Signaling Alterations in Oligodendrocytes.
Chierto E, Simon A, Castoldi F, Meffre D, Cristinziano G, Sapone F, Carrete A, Borderie D, Etienne F, Rannou F, Morrison B 3rd, Massaad C, Jafarian-Tehrani M. Chierto E, et al. Among authors: carrete a. Mol Neurobiol. 2019 Jun;56(6):4231-4248. doi: 10.1007/s12035-018-1372-6. Epub 2018 Oct 8. Mol Neurobiol. 2019. PMID: 30298339 Free PMC article.