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Targeted deletion of the extracellular signal-regulated protein kinase 5 attenuates hypertrophic response and promotes pressure overload-induced apoptosis in the heart.
Kimura TE, Jin J, Zi M, Prehar S, Liu W, Oceandy D, Abe J, Neyses L, Weston AH, Cartwright EJ, Wang X. Kimura TE, et al. Among authors: cartwright ej. Circ Res. 2010 Mar 19;106(5):961-70. doi: 10.1161/CIRCRESAHA.109.209320. Epub 2010 Jan 14. Circ Res. 2010. PMID: 20075332 Free PMC article.
Mitogen-activated protein kinase kinase 4 deficiency in cardiomyocytes causes connexin 43 reduction and couples hypertrophic signals to ventricular arrhythmogenesis.
Zi M, Kimura TE, Liu W, Jin J, Higham J, Kharche S, Hao G, Shi Y, Shen W, Prehar S, Mironov A, Neyses L, Bierhuizen MF, Boyett MR, Zhang H, Lei M, Cartwright EJ, Wang X. Zi M, et al. Among authors: cartwright ej. J Biol Chem. 2011 May 20;286(20):17821-30. doi: 10.1074/jbc.M111.228791. Epub 2011 Mar 28. J Biol Chem. 2011. PMID: 21454599 Free PMC article. No abstract available.
Plasma membrane calcium pump (PMCA4)-neuronal nitric-oxide synthase complex regulates cardiac contractility through modulation of a compartmentalized cyclic nucleotide microdomain.
Mohamed TMA, Oceandy D, Zi M, Prehar S, Alatwi N, Wang Y, Shaheen MA, Abou-Leisa R, Schelcher C, Hegab Z, Baudoin F, Emerson M, Mamas M, Di Benedetto G, Zaccolo M, Lei M, Cartwright EJ, Neyses L. Mohamed TMA, et al. J Biol Chem. 2011 Dec 2;286(48):41520-41529. doi: 10.1074/jbc.M111.290411. Epub 2011 Sep 29. J Biol Chem. 2011. PMID: 21965681 Free PMC article.
Pak1 as a novel therapeutic target for antihypertrophic treatment in the heart.
Liu W, Zi M, Naumann R, Ulm S, Jin J, Taglieri DM, Prehar S, Gui J, Tsui H, Xiao RP, Neyses L, Solaro RJ, Ke Y, Cartwright EJ, Lei M, Wang X. Liu W, et al. Circulation. 2011 Dec 13;124(24):2702-15. doi: 10.1161/CIRCULATIONAHA.111.048785. Epub 2011 Nov 14. Circulation. 2011. PMID: 22082674 Free PMC article.
265 results