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A 6-month, randomized, double-masked, placebo-controlled study evaluating the effects of the protein kinase C-beta inhibitor ruboxistaurin on skin microvascular blood flow and other measures of diabetic peripheral neuropathy.
Casellini CM, Barlow PM, Rice AL, Casey M, Simmons K, Pittenger G, Bastyr EJ 3rd, Wolka AM, Vinik AI. Casellini CM, et al. Diabetes Care. 2007 Apr;30(4):896-902. doi: 10.2337/dc06-1699. Diabetes Care. 2007. PMID: 17392551 Clinical Trial.
Diabetic neuropathy.
Vinik AI, Nevoret ML, Casellini C, Parson H. Vinik AI, et al. Endocrinol Metab Clin North Am. 2013 Dec;42(4):747-87. doi: 10.1016/j.ecl.2013.06.001. Endocrinol Metab Clin North Am. 2013. PMID: 24286949 Review.
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