Castriota GA - Search Results

1

Design and synthesis of a new class of malonyl-CoA decarboxylase inhibitors with anti-obesity and anti-diabetic activities.

Tang H, Yan Y, Feng Z, de Jesus RK, Yang L, Levorse DA, Owens KA, Akiyama TE, Bergeron R, Castriota GA, Doebber TW, Ellsworth KP, Lassman ME, Li C, Wu MS, Zhang BB, Chapman KT, Mills SG, Berger JP, Pasternak A. Tang H, et al. Among authors: castriota ga. Bioorg Med Chem Lett. 2010 Oct 15;20(20):6088-92. doi: 10.1016/j.bmcl.2010.08.047. Epub 2010 Aug 20. Bioorg Med Chem Lett. 2010. PMID: 20832306

2

Benzimidazolones: a new class of selective peroxisome proliferator-activated receptor γ (PPARγ) modulators.

Liu W, Lau F, Liu K, Wood HB, Zhou G, Chen Y, Li Y, Akiyama TE, Castriota G, Einstein M, Wang C, McCann ME, Doebber TW, Wu M, Chang CH, McNamara L, McKeever B, Mosley RT, Berger JP, Meinke PT. Liu W, et al. J Med Chem. 2011 Dec 22;54(24):8541-54. doi: 10.1021/jm201061j. Epub 2011 Nov 28. J Med Chem. 2011. PMID: 22070604

3

RNAi-mediated germline knockdown of FABP4 increases body weight but does not improve the deranged nutrient metabolism of diet-induced obese mice.

Yang R, Castriota G, Chen Y, Cleary MA, Ellsworth K, Shin MK, Tran JL, Vogt TF, Wu M, Xu S, Yang X, Zhang BB, Berger JP, Qureshi SA. Yang R, et al. Int J Obes (Lond). 2011 Feb;35(2):217-25. doi: 10.1038/ijo.2010.128. Epub 2010 Jul 6. Int J Obes (Lond). 2011. PMID: 20603627 Free PMC article.

4

Development of a novel GLUT4 translocation assay for identifying potential novel therapeutic targets for insulin sensitization.

Liu F, Dallas-Yang Q, Castriota G, Fischer P, Santini F, Ferrer M, Li J, Akiyama TE, Berger JP, Zhang BB, Jiang G. Liu F, et al. Biochem J. 2009 Mar 1;418(2):413-20. doi: 10.1042/BJ20082051. Biochem J. 2009. PMID: 19035854

5

The differential interactions of peroxisome proliferator-activated receptor gamma ligands with Tyr473 is a physical basis for their unique biological activities.

Einstein M, Akiyama TE, Castriota GA, Wang CF, McKeever B, Mosley RT, Becker JW, Moller DE, Meinke PT, Wood HB, Berger JP. Einstein M, et al. Among authors: castriota ga. Mol Pharmacol. 2008 Jan;73(1):62-74. doi: 10.1124/mol.107.041202. Epub 2007 Oct 16. Mol Pharmacol. 2008. PMID: 17940191

6

Peroxisome proliferator-activated receptor gamma agonists inhibit adipocyte expression of alpha1-acid glycoprotein.

Castriota G, Thompson GM, Lin Y, Scherer PE, Moller DE, Berger JP. Castriota G, et al. Cell Biol Int. 2007 Jun;31(6):586-91. doi: 10.1016/j.cellbi.2006.11.033. Epub 2006 Dec 15. Cell Biol Int. 2007. PMID: 17240171

7

A genome-wide siRNA screen to identify modulators of insulin sensitivity and gluconeogenesis.

Yang R, Lacson RG, Castriota G, Zhang XD, Liu Y, Zhao W, Einstein M, Camargo LM, Qureshi S, Wong KK, Zhang BB, Ferrer M, Berger JP. Yang R, et al. PLoS One. 2012;7(5):e36384. doi: 10.1371/journal.pone.0036384. Epub 2012 May 9. PLoS One. 2012. PMID: 22590537 Free PMC article.

8

Inhibition of Factor XIa Reduces the Frequency of Cerebral Microembolic Signals Derived from Carotid Arterial Thrombosis in Rabbits.

Wang X, Kurowski S, Wu W, Castriota GA, Zhou X, Chu L, Ellsworth KP, Chu D, Edmondson S, Ali A, Andre P, Seiffert D, Erion M, Gutstein DE, Chen Z. Wang X, et al. Among authors: castriota ga. J Pharmacol Exp Ther. 2017 Mar;360(3):476-483. doi: 10.1124/jpet.116.238600. Epub 2016 Dec 29. J Pharmacol Exp Ther. 2017. PMID: 28035007

9

Differential anti-thrombotic benefit and bleeding risk profiles of antagonists of protease-activated receptor 1 and 4 in Cynomolgus Macaques.

Wickham LA, Sitko G, Stranieri-Michener M, Handt L, Basso A, Fried S, Chu L, Maderia M, Owens K, Castriota G, Chen Z, Metzger JM, Imbriglio J, Wang X, Cai TQ. Wickham LA, et al. Thromb Res. 2016 Sep;145:133-9. doi: 10.1016/j.thromres.2016.06.007. Epub 2016 Jun 11. Thromb Res. 2016. PMID: 27318768

10

Peroxisome proliferator-activated receptor gamma agonism increases the capacity for sympathetically mediated thermogenesis in lean and ob/ob mice.

Sell H, Berger JP, Samson P, Castriota G, Lalonde J, Deshaies Y, Richard D. Sell H, et al. Endocrinology. 2004 Aug;145(8):3925-34. doi: 10.1210/en.2004-0321. Epub 2004 May 6. Endocrinology. 2004. PMID: 15131020

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