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A Trimeric HIV-1 Envelope gp120 Immunogen Induces Potent and Broad Anti-V1V2 Loop Antibodies against HIV-1 in Rabbits and Rhesus Macaques.
J Virol. 2018 Feb 12;92(5):e01796-17. doi: 10.1128/JVI.01796-17. Print 2018 Mar 1.
J Virol. 2018.
PMID: 29237847
Free PMC article.
Oral Immunization with a Recombinant Lactococcus lactis-Expressing HIV-1 Antigen on Group A Streptococcus Pilus Induces Strong Mucosal Immunity in the Gut.
Chamcha V, Jones A, Quigley BR, Scott JR, Amara RR.
Chamcha V, et al.
J Immunol. 2015 Nov 15;195(10):5025-34. doi: 10.4049/jimmunol.1501243. Epub 2015 Oct 19.
J Immunol. 2015.
PMID: 26482408
Free PMC article.
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Strong, but Age-Dependent, Protection Elicited by a Deoxyribonucleic Acid/Modified Vaccinia Ankara Simian Immunodeficiency Virus Vaccine.
Chamcha V, Kannanganat S, Gangadhara S, Nabi R, Kozlowski PA, Montefiori DC, LaBranche CC, Wrammert J, Keele BF, Balachandran H, Sahu S, Lifton M, Santra S, Basu R, Moss B, Robinson HL, Amara RR.
Chamcha V, et al.
Open Forum Infect Dis. 2016 Feb 11;3(1):ofw034. doi: 10.1093/ofid/ofw034. eCollection 2016 Jan.
Open Forum Infect Dis. 2016.
PMID: 27006959
Free PMC article.
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Strong TH1-biased CD4 T cell responses are associated with diminished SIV vaccine efficacy.
Chamcha V, Reddy PBJ, Kannanganat S, Wilkins C, Gangadhara S, Velu V, Green R, Law GL, Chang J, Bowen JR, Kozlowski PA, Lifton M, Santra S, Legere T, Chea LS, Chennareddi L, Yu T, Suthar MS, Silvestri G, Derdeyn CA, Gale M Jr, Villinger F, Hunter E, Amara RR.
Chamcha V, et al.
Sci Transl Med. 2019 Nov 20;11(519):eaav1800. doi: 10.1126/scitranslmed.aav1800.
Sci Transl Med. 2019.
PMID: 31748228
Free PMC article.
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O-mannosylation of the Mycobacterium tuberculosis adhesin Apa is crucial for T cell antigenicity during infection but is expendable for protection.
Nandakumar S, Kannanganat S, Dobos KM, Lucas M, Spencer JS, Fang S, McDonald MA, Pohl J, Birkness K, Chamcha V, Ramirez MV, Plikaytis BB, Posey JE, Amara RR, Sable SB.
Nandakumar S, et al. Among authors: chamcha v.
PLoS Pathog. 2013;9(10):e1003705. doi: 10.1371/journal.ppat.1003705. Epub 2013 Oct 10.
PLoS Pathog. 2013.
PMID: 24130497
Free PMC article.
Clinical Trial.
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Development of a robust cell-based potency assay for a coxsackievirus A21 oncolytic virotherapy.
Chamcha V, He L, Jenny Xu, Swartz AR, Green-Trexler E, Gurney K, McNeely T.
Chamcha V, et al.
Heliyon. 2024 Mar 20;10(7):e28414. doi: 10.1016/j.heliyon.2024.e28414. eCollection 2024 Apr 15.
Heliyon. 2024.
PMID: 38560158
Free PMC article.
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High Doses of GM-CSF Inhibit Antibody Responses in Rectal Secretions and Diminish Modified Vaccinia Ankara/Simian Immunodeficiency Virus Vaccine Protection in TRIM5α-Restrictive Macaques.
Kannanganat S, Wyatt LS, Gangadhara S, Chamcha V, Chea LS, Kozlowski PA, LaBranche CC, Chennareddi L, Lawson B, Reddy PB, Styles TM, Vanderford TH, Montefiori DC, Moss B, Robinson HL, Amara RR.
Kannanganat S, et al. Among authors: chamcha v.
J Immunol. 2016 Nov 1;197(9):3586-3596. doi: 10.4049/jimmunol.1600629. Epub 2016 Sep 28.
J Immunol. 2016.
PMID: 27683750
Free PMC article.
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