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Discovery of potent 3,5-diphenyl-1,2,4-oxadiazole sphingosine-1-phosphate-1 (S1P1) receptor agonists with exceptional selectivity against S1P2 and S1P3.
Li Z, Chen W, Hale JJ, Lynch CL, Mills SG, Hajdu R, Keohane CA, Rosenbach MJ, Milligan JA, Shei GJ, Chrebet G, Parent SA, Bergstrom J, Card D, Forrest M, Quackenbush EJ, Wickham LA, Vargas H, Evans RM, Rosen H, Mandala S. Li Z, et al. Among authors: chen w. J Med Chem. 2005 Oct 6;48(20):6169-73. doi: 10.1021/jm0503244. J Med Chem. 2005. PMID: 16190743
Design, synthesis, and evaluation of naphthalene-sulfonamide antagonists of human CCR8.
Jenkins TJ, Guan B, Dai M, Li G, Lightburn TE, Huang S, Freeze BS, Burdi DF, Jacutin-Porte S, Bennett R, Chen W, Minor C, Ghosh S, Blackburn C, Gigstad KM, Jones M, Kolbeck R, Yin W, Smith S, Cardillo D, Ocain TD, Harriman GC. Jenkins TJ, et al. Among authors: chen w. J Med Chem. 2007 Feb 8;50(3):566-84. doi: 10.1021/jm061118e. J Med Chem. 2007. PMID: 17266208
3,3-Disubstituted ethyl carbazates.
Smith WT Jr, Chen WY. Smith WT Jr, et al. Among authors: chen wy. J Med Chem. 1969 Jul;12(4):727-8. doi: 10.1021/jm00304a057. J Med Chem. 1969. PMID: 5797540 No abstract available.
Some N-sulfinylhydrazine analogs of nitrogen mustard.
Smith WT Jr, Chen WY. Smith WT Jr, et al. Among authors: chen wy. J Med Chem. 1968 May;11(3):504-5. doi: 10.1021/jm00309a021. J Med Chem. 1968. PMID: 5656487 No abstract available.
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