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Genomewide Association Study of Statin-Induced Myopathy in Patients Recruited Using the UK Clinical Practice Research Datalink.
Carr DF, Francis B, Jorgensen AL, Zhang E, Chinoy H, Heckbert SR, Bis JC, Brody JA, Floyd JS, Psaty BM, Molokhia M, Lapeyre-Mestre M, Conforti A, Alfirevic A, van Staa T, Pirmohamed M. Carr DF, et al. Among authors: chinoy h. Clin Pharmacol Ther. 2019 Dec;106(6):1353-1361. doi: 10.1002/cpt.1557. Epub 2019 Jul 31. Clin Pharmacol Ther. 2019. PMID: 31220337 Free PMC article.
Phenotype standardization for statin-induced myotoxicity.
Alfirevic A, Neely D, Armitage J, Chinoy H, Cooper RG, Laaksonen R, Carr DF, Bloch KM, Fahy J, Hanson A, Yue QY, Wadelius M, Maitland-van Der Zee AH, Voora D, Psaty BM, Palmer CN, Pirmohamed M. Alfirevic A, et al. Among authors: chinoy h. Clin Pharmacol Ther. 2014 Oct;96(4):470-6. doi: 10.1038/clpt.2014.121. Epub 2014 Jun 4. Clin Pharmacol Ther. 2014. PMID: 24897241 Free PMC article.
GATM gene variants and statin myopathy risk.
Carr DF, Alfirevic A, Johnson R, Chinoy H, van Staa T, Pirmohamed M. Carr DF, et al. Among authors: chinoy h. Nature. 2014 Sep 18;513(7518):E1. doi: 10.1038/nature13628. Nature. 2014. PMID: 25230669 No abstract available.
Pharmacogenomics of statin-related myopathy: Meta-analysis of rare variants from whole-exome sequencing.
Floyd JS, Bloch KM, Brody JA, Maroteau C, Siddiqui MK, Gregory R, Carr DF, Molokhia M, Liu X, Bis JC, Ahmed A, Liu X, Hallberg P, Yue QY, Magnusson PKE, Brisson D, Wiggins KL, Morrison AC, Khoury E, McKeigue P, Stricker BH, Lapeyre-Mestre M, Heckbert SR, Gallagher AM, Chinoy H, Gibbs RA, Bondon-Guitton E, Tracy R, Boerwinkle E, Gaudet D, Conforti A, van Staa T, Sitlani CM, Rice KM, Maitland-van der Zee AH, Wadelius M, Morris AP, Pirmohamed M, Palmer CAN, Psaty BM, Alfirevic A; PREDICTION-ADR Consortium and EUDRAGENE. Floyd JS, et al. Among authors: chinoy h. PLoS One. 2019 Jun 26;14(6):e0218115. doi: 10.1371/journal.pone.0218115. eCollection 2019. PLoS One. 2019. PMID: 31242253 Free PMC article.
The protein tyrosine phosphatase N22 gene is associated with juvenile and adult idiopathic inflammatory myopathy independent of the HLA 8.1 haplotype in British Caucasian patients.
Chinoy H, Platt H, Lamb JA, Betteridge Z, Gunawardena H, Fertig N, Varsani H, Davidson J, Oddis CV, McHugh NJ, Wedderburn LR, Ollier WE, Cooper RG; UK Adult Onset Myositis Immunogenetic Collaboration and the Juvenile Dermatomyositis Research Group. Chinoy H, et al. Arthritis Rheum. 2008 Oct;58(10):3247-54. doi: 10.1002/art.23900. Arthritis Rheum. 2008. PMID: 18821667 Free PMC article.
Genetic association study of NF-κB genes in UK Caucasian adult and juvenile onset idiopathic inflammatory myopathy.
Chinoy H, Li CK, Platt H, Fertig N, Varsani H, Gunawardena H, Betteridge Z, Oddis CV, McHugh NJ, Wedderburn LR, Ollier WE, Cooper RG; UK Adult Onset Myositis Immunogenetic Consortium and UK Juvenile Dermatomyositis Research Group. Chinoy H, et al. Rheumatology (Oxford). 2012 May;51(5):794-9. doi: 10.1093/rheumatology/ker379. Epub 2011 Dec 30. Rheumatology (Oxford). 2012. PMID: 22210660 Free PMC article.
Genome-wide association study of dermatomyositis reveals genetic overlap with other autoimmune disorders.
Miller FW, Cooper RG, Vencovský J, Rider LG, Danko K, Wedderburn LR, Lundberg IE, Pachman LM, Reed AM, Ytterberg SR, Padyukov L, Selva-O'Callaghan A, Radstake TR, Isenberg DA, Chinoy H, Ollier WE, O'Hanlon TP, Peng B, Lee A, Lamb JA, Chen W, Amos CI, Gregersen PK; Myositis Genetics Consortium. Miller FW, et al. Among authors: chinoy h. Arthritis Rheum. 2013 Dec;65(12):3239-47. doi: 10.1002/art.38137. Arthritis Rheum. 2013. PMID: 23983088 Free PMC article.
242 results