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Genome-wide association study implicates immune dysfunction in the development of Hodgkin lymphoma.
Sud A, Thomsen H, Orlando G, Försti A, Law PJ, Broderick P, Cooke R, Hariri F, Pastinen T, Easton DF, Pharoah PDP, Dunning AM, Peto J, Canzian F, Eeles R, Kote-Jarai Z, Muir K, Pashayan N, Campa D; PRACTICAL Consortium; Hoffmann P, Nöthen MM, Jöckel KH, von Strandmann EP, Swerdlow AJ, Engert A, Orr N, Hemminki K, Houlston RS. Sud A, et al. Among authors: cooke r. Blood. 2018 Nov 8;132(19):2040-2052. doi: 10.1182/blood-2018-06-855296. Epub 2018 Sep 7. Blood. 2018. PMID: 30194254 Free PMC article.
A genome-wide association study of Hodgkin's lymphoma identifies new susceptibility loci at 2p16.1 (REL), 8q24.21 and 10p14 (GATA3).
Enciso-Mora V, Broderick P, Ma Y, Jarrett RF, Hjalgrim H, Hemminki K, van den Berg A, Olver B, Lloyd A, Dobbins SE, Lightfoot T, van Leeuwen FE, Försti A, Diepstra A, Broeks A, Vijayakrishnan J, Shield L, Lake A, Montgomery D, Roman E, Engert A, von Strandmann EP, Reiners KS, Nolte IM, Smedby KE, Adami HO, Russell NS, Glimelius B, Hamilton-Dutoit S, de Bruin M, Ryder LP, Molin D, Sorensen KM, Chang ET, Taylor M, Cooke R, Hofstra R, Westers H, van Wezel T, van Eijk R, Ashworth A, Rostgaard K, Melbye M, Swerdlow AJ, Houlston RS. Enciso-Mora V, et al. Among authors: cooke r. Nat Genet. 2010 Dec;42(12):1126-1130. doi: 10.1038/ng.696. Epub 2010 Oct 31. Nat Genet. 2010. PMID: 21037568 Free PMC article.
Multiple Hodgkin lymphoma-associated loci within the HLA region at chromosome 6p21.3.
Moutsianas L, Enciso-Mora V, Ma YP, Leslie S, Dilthey A, Broderick P, Sherborne A, Cooke R, Ashworth A, Swerdlow AJ, McVean G, Houlston RS. Moutsianas L, et al. Among authors: cooke r. Blood. 2011 Jul 21;118(3):670-4. doi: 10.1182/blood-2011-03-339630. Epub 2011 May 19. Blood. 2011. PMID: 21596858 Free article.
FGFR2 genotype and risk of radiation-associated breast cancer in Hodgkin lymphoma.
Ma YP, van Leeuwen FE, Cooke R, Broeks A, Enciso-Mora V, Olver B, Lloyd A, Broderick P, Russell NS, Janus C, Ashworth A, Houlston RS, Swerdlow AJ. Ma YP, et al. Among authors: cooke r. Blood. 2012 Jan 26;119(4):1029-31. doi: 10.1182/blood-2011-10-383380. Epub 2011 Dec 5. Blood. 2012. PMID: 22144180 Free article.
Variation at 3p24.1 and 6q23.3 influences the risk of Hodgkin's lymphoma.
Frampton M, da Silva Filho MI, Broderick P, Thomsen H, Försti A, Vijayakrishnan J, Cooke R, Enciso-Mora V, Hoffmann P, Nöthen MM, Lloyd A, Holroyd A, Eisele L, Jöckel KH, Ponader S, von Strandmann EP, Lightfoot T, Roman E, Lake A, Montgomery D, Jarrett RF, Swerdlow AJ, Engert A, Hemminki K, Houlston RS. Frampton M, et al. Among authors: cooke r. Nat Commun. 2013;4:2549. doi: 10.1038/ncomms3549. Nat Commun. 2013. PMID: 24149102 Free PMC article.
Genome-wide association analysis of chronic lymphocytic leukaemia, Hodgkin lymphoma and multiple myeloma identifies pleiotropic risk loci.
Law PJ, Sud A, Mitchell JS, Henrion M, Orlando G, Lenive O, Broderick P, Speedy HE, Johnson DC, Kaiser M, Weinhold N, Cooke R, Sunter NJ, Jackson GH, Summerfield G, Harris RJ, Pettitt AR, Allsup DJ, Carmichael J, Bailey JR, Pratt G, Rahman T, Pepper C, Fegan C, von Strandmann EP, Engert A, Försti A, Chen B, Filho MI, Thomsen H, Hoffmann P, Noethen MM, Eisele L, Jöckel KH, Allan JM, Swerdlow AJ, Goldschmidt H, Catovsky D, Morgan GJ, Hemminki K, Houlston RS. Law PJ, et al. Among authors: cooke r. Sci Rep. 2017 Jan 23;7:41071. doi: 10.1038/srep41071. Sci Rep. 2017. PMID: 28112199 Free PMC article.
Genome-wide association study of classical Hodgkin lymphoma identifies key regulators of disease susceptibility.
Sud A, Thomsen H, Law PJ, Försti A, Filho MIDS, Holroyd A, Broderick P, Orlando G, Lenive O, Wright L, Cooke R, Easton D, Pharoah P, Dunning A, Peto J, Canzian F, Eeles R, Kote-Jarai Z, Muir K, Pashayan N; PRACTICAL consortium; Hoffmann P, Nöthen MM, Jöckel KH, Strandmann EPV, Lightfoot T, Kane E, Roman E, Lake A, Montgomery D, Jarrett RF, Swerdlow AJ, Engert A, Orr N, Hemminki K, Houlston RS. Sud A, et al. Among authors: cooke r. Nat Commun. 2017 Dec 1;8(1):1892. doi: 10.1038/s41467-017-00320-1. Nat Commun. 2017. PMID: 29196614 Free PMC article.
Genetic susceptibility to radiation-induced breast cancer after Hodgkin lymphoma.
Opstal-van Winden AWJ, de Haan HG, Hauptmann M, Schmidt MK, Broeks A, Russell NS, Janus CPM, Krol ADG, van der Baan FH, De Bruin ML, van Eggermond AM, Dennis J, Anton-Culver H, Haiman CA, Sawyer EJ, Cox A, Devilee P, Hooning MJ, Peto J, Couch FJ, Pharoah P, Orr N, Easton DF, Aleman BMP, Strong LC, Bhatia S, Cooke R, Robison LL, Swerdlow AJ, van Leeuwen FE. Opstal-van Winden AWJ, et al. Among authors: cooke r. Blood. 2019 Mar 7;133(10):1130-1139. doi: 10.1182/blood-2018-07-862607. Epub 2018 Dec 20. Blood. 2019. PMID: 30573632 Free PMC article.
IRF4 polymorphism rs872071 and risk of Hodgkin lymphoma.
Broderick P, Cunningham D, Vijayakrishnan J, Cooke R, Ashworth A, Swerdlow A, Houlston R. Broderick P, et al. Among authors: cooke r. Br J Haematol. 2010 Feb;148(3):413-5. doi: 10.1111/j.1365-2141.2009.07946.x. Epub 2009 Oct 5. Br J Haematol. 2010. PMID: 19804451 Free article.
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