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Integrative genomics reveals novel molecular pathways and gene networks for coronary artery disease.
PLoS Genet. 2014 Jul 17;10(7):e1004502. doi: 10.1371/journal.pgen.1004502. eCollection 2014 Jul.
PLoS Genet. 2014.
PMID: 25033284
Free PMC article.
The majority of the heritability of coronary artery disease (CAD) remains unexplained, despite recent successes of genome-wide association studies (GWAS) in identifying novel susceptibility loci. ...Towards this end, we integrated 14 GWAS from the CARDIoGRAM Consortium and …
The majority of the heritability of coronary artery disease (CAD) remains unexplained, despite recent successes of genome-wide associ …
Genome-wide association study in Han Chinese identifies four new susceptibility loci for coronary artery disease.
Lu X, Wang L, Chen S, He L, Yang X, Shi Y, Cheng J, Zhang L, Gu CC, Huang J, Wu T, Ma Y, Li J, Cao J, Chen J, Ge D, Fan Z, Li Y, Zhao L, Li H, Zhou X, Chen L, Liu D, Chen J, Duan X, Hao Y, Wang L, Lu F, Liu Z, Yao C, Shen C, Pu X, Yu L, Fang X, Xu L, Mu J, Wu X, Zheng R, Wu N, Zhao Q, Li Y, Liu X, Wang M, Yu D, Hu D, Ji X, Guo D, Sun D, Wang Q, Yang Y, Liu F, Mao Q, Liang X, Ji J, Chen P, Mo X, Li D, Chai G, Tang Y, Li X, Du Z, Liu X, Dou C, Yang Z, Meng Q, Wang D, Wang R, Yang J, Schunkert H, Samani NJ, Kathiresan S, Reilly MP, Erdmann J; Coronary ARtery DIsease Genome-Wide Replication And Meta-Analysis (CARDIoGRAM) Consortium; Peng X, Wu X, Liu D, Yang Y, Chen R, Qiang B, Gu D.
Lu X, et al.
Nat Genet. 2012 Jul 1;44(8):890-4. doi: 10.1038/ng.2337.
Nat Genet. 2012.
PMID: 22751097
Free PMC article.
We identify four new loci for coronary artery disease that reached the threshold of genome-wide significance (P < 5 10(-8)). ...These findings provide new insights into pathways contributing to the susceptibility for coronary artery disease in the Chinese Han pop
…We identify four new loci for coronary artery disease that reached the threshold of genome-wide significance (P < 5 10(-8)). ...Th
…
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